Kiss L., James L. C.
The molecular mechanisms that drive intracellular neutralization by the antibody-receptor and RING E3 ligase TRIM21
Seminars in Cell & Developmental Biology 126:99-107. June 2022DOI: 10.1016/j.semcdb.2021.11.005
PMID: 34823983
PMCID:
Date of Paper: 01/06/2022
Division: Protein & Nucleic Acid ChemistryNewman A., Luisi B.,
Kiyoshi Nagai. 25 June 1949—27 September 2019
Biographical Memoirs of Fellows of the Royal Society 72:275-291. June 2022DOI: 10.1098/rsbm.2021.0043
PMID:
PMCID:
Date of Paper: 01/06/2022
Division: Structural StudiesKampjut D., Sazanov L. A.
Structure of respiratory complex I - An emerging blueprint for the mechanism
Current Opinion in Structural Biology 74:102350. June 2022DOI: 10.1016/j.sbi.2022.102350
PMID: 35316665
PMCID: PMC7613608
Date of Paper: 01/06/2022
Division: NeurobiologyMieszczanek J., Strutt H., Rutherford T. J., Strutt D., Bienz M., Gammons M. V.
Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling
Journal of Cell Science 135(11):jcs259547. June 2022DOI: 10.1242/jcs.259547
PMID: 35542970
PMCID: PMC9234668
Date of Paper: 01/06/2022
Division: Protein & Nucleic Acid ChemistryRzechorzek N. M., et al (including O'Neill J. S.)
A daily temperature rhythm in the human brain predicts survival after brain injury
Brain : a Journal of Neurology 145(6): 2031-2048. June 2022DOI: 10.1093/brain/awab466
PMID: 35691613
PMCID: PMC9336587
Date of Paper: 01/06/2022
Division: Cell BiologyMcCoy M. A., Spicer D., Wells N., Hoogewijs K., Fiedler M., Baud M. G. J.
Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale
Journal of Medicinal Chemistry 65(10):7246-7261. 26 May 2022DOI: 10.1021/acs.jmedchem.2c00228
PMID: 35581674
PMCID: PMC9150122
Date of Paper: 26/05/2022
Division: Protein & Nucleic Acid ChemistryPatton A. P., Smyllie N. J., Chesham J. E., Hastings M. H.
Astrocytes sustain circadian oscillation and bidirectionally determine circadian period, but do not regulate circadian phase in the suprachiasmatic nucleus
Journal of Neuroscience e-pub: published online 23 May 2022DOI: 10.1523/jneurosci.2337-21.2022
PMID: 35610047
PMCID: PMC9295834
Date of Paper: 23/05/2022
Division: NeurobiologyFermie J., de Jager L., Foster H. E., Veenendaal T., de Heus C., van Dijk S., Ten Brink C., Oorschot V., Yang L., Li W., Müller W. H., Howes S., Carter A. P., Förster F., Posthuma G., Gerritsen H. C., Klumperman J., Liv N.
Bimodal endocytic probe for three-dimensional correlative light and electron microscopy
Cell Reports Methods 2(5):100220. 23 May 2022DOI: 10.1016/j.crmeth.2022.100220
PMID: 35637912
PMCID: PMC9142762
Date of Paper: 23/05/2022
Division: Structural StudiesKübler I. C., Kretzschmar J., Brankatschk M., Sandoval-Guzmán T.
Local problems need global solutions: The metabolic needs of regenerating organisms
Wound Repair and Regeneration e-pub: published online 21 May 2022DOI: 10.1111/wrr.13029
PMID: 35596643
PMCID: PMC7613859
Date of Paper: 21/05/2022
Division: Cell BiologyYatskevich S., Muir K. W., Bellini D., Zhang Z., Yang J., Tischer T., Predin M., Dendooven T., McLaughlin S. H., Barford D.
Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome
Science 376(6595):844-852. 20 May 2022DOI: 10.1126/science.abn3810
PMID: 35420891
PMCID: PMC7612757
Date of Paper: 20/05/2022
Division: Structural StudiesKurihara N., Nakagawa R., Hirano H., Okazaki S., Tomita A., Kobayashi K., Kusakizako T., Nishizawa T., Yamashita K., Scott D. A., Nishimasu H., Nureki O.
Structure of the type V-C CRISPR-Cas effector enzyme
Molecular Cell 82(10):1865-1877.e4. 19 May 2022DOI: 10.1016/j.molcel.2022.03.006
PMID: 35366394
PMCID: PMC9522604
Date of Paper: 19/05/2022
Division: Structural StudiesBaris Y., Taylor M. R. G., Aria V., Yeeles J. T. P.
Fast and efficient DNA replication with purified human proteins
Nature 606(7912):204-210. 18 May 2022DOI: 10.1038/s41586-022-04759-1
PMID: 35585232
PMCID: PMC7613936
Date of Paper: 18/05/2022
Division: Protein & Nucleic Acid ChemistryRodríguez-Molina J. B., O'Reilly F. J., Fagarasan H., Sheekey E., Maslen S., Skehel J. M., Rappsilber J., Passmore L. A.
Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF
Molecular Cell e-pub: published online 17 May 2022DOI: 10.1016/j.molcel.2022.04.021
PMID: 35584695
PMCID: PMC9380774
Date of Paper: 17/05/2022
Division: Structural Studies, Cell Biologyde Goederen V., Vetter R., McDole K., Iber D.
Hinge point emergence in mammalian spinal neurulation
Proceedings of the National Academy of Sciences of the United States of America 119(20):e2117075119. 13 May 2022DOI: 10.1073/pnas.2117075119
PMID: 35561223
PMCID: PMC9172135
Date of Paper: 13/05/2022
Division: Cell BiologySchweighauser M., Arseni D., Bacioglu M., Huang M., Lövestam S., Shi Y., Yang Y., Zhang W., Kotecha A., Garringer H. J., Vidal R., Hallinan G. I., Newell K. L., Tarutani A., Murayama S., Miyazaki M., Saito Y., Yoshida M., Hasegawa K., Lashley T., Revesz T., Kovacs G. G., van Swieten J., Takao M., Hasegawa M., Ghetti B., Spillantini M. G., Ryskeldi-Falcon B., Murzin A. G., Goedert M., Scheres S. H. W.
Age-dependent formation of TMEM106B amyloid filaments in human brains
Nature 605(7909):310-314. 12 May 2022DOI: 10.1038/s41586-022-04650-z
PMID: 35344985
PMCID: PMC9095482
Date of Paper: 12/05/2022
Division: Neurobiology, Structural StudiesDenton A. E., Dooley J., Cinti I., Silva-Cayetano A., Fra-Bido S., Innocentin S., Hill D. L., Carr E. J., McKenzie A. N. J., Liston A., Linterman M. A.
Targeting TLR4 during vaccination boosts MAdCAM-1+ lymphoid stromal cell activation and promotes the aged germinal center response
Science Immunology 7(71):eabk0018. 6 May 2022DOI: 10.1126/sciimmunol.abk0018
PMID: 35522725
PMCID: PMC7612953
Date of Paper: 06/05/2022
Division: Protein & Nucleic Acid ChemistryHagino T., Kato T., Kasuya G., Kobayashi K., Kusakizako T., Hamamoto S., Sobajima T., Fujiwara Y., Yamashita K., Kawasaki H., Maturana A. D., Nishizawa T., Nureki O.
Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1
Nature Communications 13(1):2505. 6 May 2022DOI: 10.1038/s41467-022-30292-w
PMID: 35523970
PMCID: PMC9076864
Date of Paper: 06/05/2022
Division: Structural StudiesLi H, et al (Including Donà E., Jefferis G. S. X. E.)
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly
Science 375(6584):eabk2432. 4 March 2022DOI: 10.1126/science.abk2432
PMID: 35239393
PMCID: PMC8944923
Date of Paper: 04/05/2022
Division: NeurobiologyGuo J., Liu B., Thorikay M., Yu M., Li X., Tong Z., Salmon R. M., Read R. J., Ten Dijke P., Morrell N. W., Li W.
Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10
Nature Communications 13(1):2395. 3 May 2022DOI: 10.1038/s41467-022-30111-2
PMID: 35504921
PMCID: PMC9064986
Date of Paper: 03/05/2022
Division: Structural StudiesTuck B. J., Miller L. V. C., Katsinelos T., Smith A. E., Wilson E. L., Keeling S., Cheng S., Vaysburd M. J., Knox C., Tredgett L., Metzakopian E., James L. C., McEwan W. A.
Cholesterol determines the cytosolic entry and seeded aggregation of tau
Cell Reports 39(5):110776. 3 May 2022DOI: 10.1016/j.celrep.2022.110776
PMID: 35508140
PMCID: PMC9108550
Date of Paper: 03/05/2022
Division: Protein & Nucleic Acid ChemistryGoedert M., Spillantini M. G.
A tribute to John Q. Trojanowski (1946-2022), neuropathologist extraordinaire
Brain Pathology 32(3):e13066. May 2022DOI: 10.1111/bpa.13066
PMID: 35312135
PMCID: PMC9048512
Date of Paper: 01/05/2022
Division: NeurobiologyFoss S., Jonsson A., Bottermann M., Watkinson R., Lode H. E., McAdam M. B., Michaelsen T. E., Sandlie I., James L. C., Andersen J. T.
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
Science Immunology 7(70):eabj1640. 29 April 2022DOI: 10.1126/sciimmunol.abj1640
PMID: 35486676
PMCID: PMC7614286
Date of Paper: 29/04/2022
Division: Protein & Nucleic Acid ChemistryZaccai N. R., Kadlecova Z., Dickson V. K., Korobchevskaya K., Kamenicky J., Kovtun O., Umasankar P. K., Wrobel A. G., Kaufman J. G. G., Gray S. R., Qu K., Evans P. R., Fritzsche M., Sroubek F., Höning S., Briggs J. A. G., Kelly B. T., Owen D. J., Traub L. M.
FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P2-dependent switch
Science Advances 8(17):eabn2018. 29 April 2022DOI: 10.1126/sciadv.abn2018
PMID: 35486718
PMCID: PMC9054013
Date of Paper: 29/04/2022
Division: Structural StudiesChoi H. K., Kang H., Lee C., Kim H. G., Phillips B. P., Park S., Tumescheit C., Kim S. A., Lee H., Roh S. H., Hong H., Steinegger M., Im W., Miller E. A., Choi H. J., Yoon T. Y.
Evolutionary balance between foldability and functionality of a glucose transporter
Nature Chemical Biology e-pub: published online 28 April 2022DOI: 10.1038/s41589-022-01002-w
PMID: 35484435
PMCID: PMC7612945
Date of Paper: 28/04/2022
Division: Cell BiologyHuynh M. S., Hooda Y., Li Y. R., Jagielnicki M., Lai C. C., Moraes T. F.
Reconstitution of surface lipoprotein translocation through the Slam translocon
Elife 11:e72822. 27 April 2022DOI: 10.7554/elife.72822
PMID: 35475756
PMCID: PMC9090332
Date of Paper: 27/04/2022
Division: Cell Biology