Kishi K. E., Kim Y. S., Fukuda M., Inoue M., Kusakizako T., Wang P. Y., Ramakrishnan C., Byrne E. F. X., Thadhani E., Paggi J. M., Matsui T. E., Yamashita K., Nagata T., Konno M., Quirin S., Lo M., Benster T., Uemura T., Liu K., Shibata M., Nomura N., Iwata S., Nureki O., Dror R. O., Inoue K., Deisseroth K., Kato H. E.
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
Cell 185(4):672-689.e23. 17 February 2022DOI: 10.1016/j.cell.2022.01.007
PMID: 35114111
PMCID: PMC7612760
Date of Paper: 17/02/2022
Division: Structural StudiesQian P, et al (including Naydenova K., Russo C. J.)
2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem
Science Advances 8(7):eabk3139. 16 February 2022DOI: 10.1126/sciadv.abk3139
PMID: 35171663
PMCID: PMC8849296
Date of Paper: 16/02/2022
Division: Structural StudiesKrzyzosiak A., Pitera A. P., Bertolotti A.
An Overview of Methods for Detecting eIF2α Phosphorylation and the Integrated Stress Response
Methods in Molecular Biology 2428:3-18. 16 February 2022DOI: 10.1007/978-1-0716-1975-9_1
PMID: 35171470
PMCID:
Date of Paper: 16/02/2022
Division: NeurobiologyBarman T. K., Huber V. C., Bonin J. L., Califano D., Salmon S. L., McKenzie A. N. J., Metzger D. W.
Viral PB1-F2 and host IFN-γ guide ILC2 and T cell activity during influenza virus infection
Proceedings of the National Academy of Sciences of the United States of America 119(8):e2118535119. 15 February 2022DOI: 10.1073/pnas.2118535119
PMID: 35169077
PMCID: PMC8872759
Date of Paper: 15/02/2022
Division: Protein & Nucleic Acid ChemistryUmansky C., Morellato A. E., Rieckher M., Scheidegger M. A., Martinefski M. R., Fernández G. A., Pak O., Kolesnikova K., Reingruber H., Bollini M., Crossan G. P., Sommer N., Monge M. E., Schumacher B., Pontel L. B.
Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity
Nature Communications 13(1):745. 8 February 2022DOI: 10.1038/s41467-022-28242-7
PMID: 35136057
PMCID: PMC8827065
Date of Paper: 08/02/2022
Division: Protein & Nucleic Acid ChemistryHerguedas B., Kohegyi B. K., Dohrke J. N., Watson J. F., Zhang D., Ho H., Shaikh S. A., Lape R., Krieger J. M., Greger I. H.
Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor
Nature Communications 13(1):734. 8 February 2022DOI: 10.1038/s41467-022-28404-7
PMID: 35136046
PMCID: PMC8826358
Date of Paper: 08/02/2022
Division: NeurobiologyMoore P. B., Hendrickson W. A., Henderson R., Brunger A. T.
The protein-folding problem: Not yet solved
Science 375(6580):507. 4 February 2022DOI: 10.1126/science.abn9422
PMID: 35113705
PMCID:
Date of Paper: 04/02/2022
Division: Structural StudiesHerdman M., von Kügelgen A., Kureisaite-Ciziene D., Duman R., El Omari K., Garman E. F., Kjaer A., Kolokouris D., Löwe J., Wagner A., Stansfeld P. J., Bharat T. A. M.
High-resolution mapping of metal ions reveals principles of surface layer assembly in Caulobacter crescentus cells
Structure 30(2):215-228.e5. 3 February 2022DOI: 10.1016/j.str.2021.10.012
PMID: 34800371
PMCID: PMC8828063
Date of Paper: 03/02/2022
Division: Structural StudiesKelava I., Chiaradia I., Pellegrini L., Kalinka A. T., Lancaster M. A.
Androgens increase excitatory neurogenic potential in human brain organoids
Nature 602(7895):112-116. 3 February 2022DOI: 10.1038/s41586-021-04330-4
PMID: 35046577
PMCID: PMC7612328
Date of Paper: 03/02/2022
Division: Cell BiologyKristoffersen E. L., Burman M., Noy A., Holliger P.
Rolling circle RNA synthesis catalysed by RNA
Elife 11:e75186. 2 February 2022DOI: 10.7554/elife.75186
PMID: 35108196
PMCID: PMC8937235
Date of Paper: 02/02/2022
Division: Protein & Nucleic Acid ChemistryPassmore L. A., Coller J.
Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression
Nature reviews. Molecular Cell Biology 23(2):93-106. 1 February 2022DOI: 10.1038/s41580-021-00417-y
PMID: 34594027
PMCID:
Date of Paper: 01/02/2022
Division: Structural StudiesHegde R. S., Keenan R. J.
The mechanisms of integral membrane protein biogenesis
Nature reviews. Molecular Cell Biology 23(2):107-124. February 2022DOI: 10.1038/s41580-021-00413-2
PMID: 34556847
PMCID:
Date of Paper: 01/02/2022
Division: Cell BiologyConley M. J., Short J. M., Burns A. M., Streetley J., Hutchings J., Bakker S. E., Power B. J., Jaffery H., Haney J., Zanetti G., Murcia P. R., Stewart M., Fearns R., Vijayakrishnan S., Bhella D.
Helical ordering of envelope-associated proteins and glycoproteins in respiratory syncytial virus
EMBO Journal 41(3):e109728. 1 February 2022DOI: 10.15252/embj.2021109728
PMID: 34935163
PMCID: PMC8804925
Date of Paper: 01/02/2022
Division: Structural StudiesAndrews B., Murphy A. E., Stofella M., Maslen S., Almeida-Souza L., Skehel J. M., Skene N. G., Sobott F., Frank R. A. W.
Multidimensional dynamics of the proteome in the neurodegenerative and aging mammalian brain
Molecular & Cellular Proteomics : MCP 21(2):100192. February 2022DOI: 10.1016/j.mcpro.2021.100192
PMID: 34979241
PMCID: PMC8816717
Date of Paper: 01/02/2022
Division: Neurobiology, Cell BiologyBoreikaite V., Elliott T. S., Chin J. W., Passmore L. A.
RBBP6 activates the pre-mRNA 3' end processing machinery in humans
Genes & Development 36(3-4):210-224. 1 February 2022DOI: 10.1101/gad.349223.121
PMID: 35177536
PMCID: PMC8887125
Date of Paper: 01/02/2022
Division: Protein & Nucleic Acid Chemistry, Structural StudiesSerna M., González-Corpas A., Cabezudo S., López-Perrote A., Degliesposti G., Zarzuela E., Skehel J. M., Muñoz J., Llorca O.
CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8
Nucleic Acids Research 50(2):1128-1146. 25 January 2022DOI: 10.1093/nar/gkab1267
PMID: 34951455
PMCID: PMC8789047
Date of Paper: 25/01/2022
Division: Cell BiologySmyllie N. J , Bagnall J , Koch A. A , Niranjan D , Polidarova L , Chesham J. E., Chin J. W., Partch C. L., Loudon A. S. I., Hastings M. H.
Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons
Proceedings of the National Academy of Sciences of the United States of America 119(4):e2113845119. 25 January 2022DOI: 10.1073/pnas.2113845119
PMID: 35046033
PMCID: PMC8795536
Date of Paper: 25/01/2022
Division: Protein & Nucleic Acid Chemistry, NeurobioogyTischer T., Yang J., Barford D.
The APC/C targets the Cep152-Cep63 complex at the centrosome to regulate mitotic spindle assembly
Journal of Cell Science 135(2). January 2022DOI: 10.1242/jcs.259273
PMID: 34878135
PMCID: PMC8917351
Date of Paper: 18/01/2022
Division: Structural StudiesChang J. H., Greene C., Frudd K., Araujo Dos Santos L., Futter C., Nichols B. J., Campbell M., Turowski P.
Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier
Cell reports. Medicine 3(1):100497. 18 January 2022DOI: 10.1016/j.xcrm.2021.100497
PMID: 35106509
PMCID: PMC8784794
Date of Paper: 18/01/2022
Division: Cell BiologyIvica J., Lape R., Sivilotti L. G.
Acidic pH reduces agonist efficacy and responses to synaptic-like glycine applications in zebrafish α1 and rat α1β recombinant glycine receptors
Journal of Physiology 600(2):333-347. 15 January 2022DOI: 10.1113/jp282171
PMID: 34802146
PMCID: PMC8836455
Date of Paper: 15/01/2022
Division: NeurobiologyYang Y., Arseni D., Zhang W., Huang M., Lövestam S., Schweighauser M., Kotecha A., Murzin A. G., Peak-Chew S. Y., Macdonald J., Lavenir I., Garringer H. J., Gelpi E., Newell K. L., Kovacs G. G., Vidal R., Ghetti B., Ryskeldi-Falcon B., Scheres S. H. W., Goedert M.
Cryo-EM structures of amyloid-β 42 filaments from human brains
Science 375(6577):167-172. 14 January 2022DOI: 10.1126/science.abm7285
PMID: 35025654
PMCID: PMC7612234
Date of Paper: 14/01/2022
Division: Structural Studies, NeurobiologyGalindo-Campos M. A,, et al (including Guilbaud G., Sale J.)
Distinct roles for PARP-1 and PARP-2 in c-Myc-driven B-cell lymphoma in mice
Blood 139(2):228-239. 13 January 2022DOI: 10.1182/blood.2021012805
PMID: 34359075
PMCID:
Date of Paper: 13/01/2022
Division: Protein & Nucleic Acid ChemistryHarris K. L., Mason S. L., Vallin B., Barker R. A.
Reduced expression of dopamine D2 receptors on astrocytes in R6/1 HD mice and HD post-mortem tissue
Neuroscience Letters 767:136289. 10 January 2022DOI: 10.1016/j.neulet.2021.136289
PMID: 34637857
PMCID: PMC9188264
Date of Paper: 10/01/2022
Division: NeurobiologyBibi Nusreen Imambocus, Fangmin Zhou, Andrey Formozov , Annika Wittich, Federico M Tenedini, Chun Hu, Kathrin Sauter, Ednilson Macarenhas Varela, Fabiana Herédia, Andreia P Casimiro, André Macedo , Philipp Schlegel, Chung-Hui Yang, Irene Miguel-Aliaga, J Simon Wiegert, Michael J Pankratz, Alisson M Gontijo, Albert Cardona, Peter Soba
A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae.
Current Biology Jan 10;32(1):149-163.e8DOI: 10.1016/j.cub.2021.10.069
PMID: 34798050
PMCID:
Date of Paper: 10/01/2022
Division: NeurobiologyRosa E Silva I., Binó L., Johnson C. M., Rutherford T. J., Neuhaus D., Andreeva A., Čajánek L., van Breugel M.
Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies
Structure 30(1):114-128.e9. 6 January 2022DOI: 10.1016/j.str.2021.08.007
PMID: 34499853
PMCID: PMC8752127
Date of Paper: 06/01/2022
Division: Structural Studies