Pellegrini L., Lancaster M. A.
Breaking the barrier: In vitro models to study choroid plexus development
Current Opinion in Cell Biology 73:41-49. December 2021DOI: 10.1016/j.ceb.2021.05.005
PMID: 34182208
PMCID:
Date of Paper: 01/12/2021
Division: Cell BiologyGattkowski E., Rutherford T. J., Möckl F., Bauche A., Sander S., Fliegert R., Tidow H.
Analysis of ligand-binding and resulting conformational changes in pyrophosphatase NUDT9
FEBS Journal 288(23):6769-6782. December 2021DOI: 10.1111/febs.16097
PMID: 34189846
PMCID:
Date of Paper: 01/12/2021
Division: Structural StudiesChandrasekaran A., Jensen P., Mohamed F. A., Lancaster M., Benros M. E., Larsen M. R., Freude K. K.
A protein-centric view of in vitro biological model systems for schizophrenia
Stem Cells 39(12):1569-1578. December 2021DOI: 10.1002/stem.3447
PMID: 34431581
PMCID:
Date of Paper: 01/12/2021
Division: Cell BiologyJenkyn-Bedford M., Jones M. L., Baris Y., Labib K. P. M., Cannone G., Yeeles J. T. P., Deegan T. D.
A Conserved Mechanism for Regulating Replisome Disassembly in Eukaryotes
Nature 600(7890):743-747. December 2021DOI: 10.1038/s41586-021-04145-3
PMID: 34700328
PMCID: PMC8695382
Date of Paper: 01/12/2021
Division: Protein & Nucleic Acid ChemistryJones M. L., Baris Y., Taylor M. R. G., Yeeles J. T. P.
Structure of a human replisome shows the organisation and interactions of a DNA replication machine
EMBO Journal 40(23):e108819. December 2021DOI: 10.15252/embj.2021108819
PMID: 34694004
PMCID: PMC8634136
Date of Paper: 01/12/2021
Division: Protein & Nucleic Acid ChemistryCrowther R. A.
Insights into neurodegeneration from electron microscopy studies
Biochemical Society Transactions 49(6):2777-2786. December 2021DOI: 10.1042/bst20210719
PMID: 34812894
PMCID: PMC8786292
Date of Paper: 01/12/2021
Division: Structural StudiesBarsotti E., Correia A., Cardona A.
Neural architectures in the light of comparative connectomics
Current Opinion in Neurobiology 71:139-149. December 2021DOI: 10.1016/j.conb.2021.10.006
PMID: 34837731
PMCID: PMC8694100
Date of Paper: 01/12/2021
Division: NeurobiologyGoedert M.
Cryo-EM structures of τ filaments from human brain
Essays in Biochemistry 65(7):949-959. December 2021DOI: 10.1042/ebc20210025
PMID: 34846514
PMCID: PMC8709893
Date of Paper: 01/12/2021
Division: NeurobiologyHodgson G., Andreeva A., Bertolotti A.
Substrate recognition determinants of human eIF2α phosphatases
Open Biology 11(12):210205. December 2021DOI: 10.1098/rsob.210205
PMID: 34847777
PMCID: PMC8633803
Date of Paper: 01/12/2021
Division: NeurobiologyStangherlin A., Seinkmane E., O'Neill J. S.
Understanding circadian regulation of mammalian cell function, protein homeostasis, and metabolism
Current Opinion in Systems Biology 28:None. December 2021DOI: 10.1016/j.coisb.2021.100391
PMID: 34950808
PMCID: PMC8660647
Date of Paper: 01/12/2021
Division: Cell BiologyBen-Tal N., Kihara D., Pandurangan A. P.
Editorial: Computational Approaches to Study the Impact of Mutations on Disease and Drug Resistance
Frontiers in Molecular Biosciences 8:813552. December 2021DOI: 10.3389/fmolb.2021.813552
PMID: 34957223
PMCID: MC8697714
Date of Paper: 01/12/2021
Division: Structural StudiesRamakrishnan V., Henderson R.
Thomas Arthur Steitz. 23 August 1940—9 October 2018
Biographical Memoirs of Fellows of the Royal SocietyDOI: 10.1098/rsbm.2021.0029
PMID:
PMCID:
Date of Paper: 01/12/2021
Division: Structural StudiesMacdonald J. A., Chen J. L., Masuda-Suzukake M., Schweighauser M., Jaunmuktane Z., Warner T., Holton J. L., Grossman A., Berks R., Lavenir I., Goedert M.
Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds
Acta Neuropathologica Communications 9(1):189. 24 November 2021DOI: 10.1186/s40478-021-01291-7
PMID: 34819144
PMCID: PMC8611835
Date of Paper: 24/11/2021
Division: NeurobiologyStangherlin A., Watson J. L., Wong D. C. S., Barbiero S., Zeng A., Seinkmane E., Chew S. P., Beale A. D., Hayter E. A., Guna A., Inglis A. J., Putker M., Bartolami E., Matile S., Lequeux N., Pons T., Day J., van Ooijen G., Voorhees R. M., Bechtold D. A., Derivery E., Edgar R. S., Newham P., O'Neill J. S.
Publisher Correction: Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology
Nature Communications 12(1):6988. 24 November 2021DOI: 10.1038/s41467-021-26725-7
PMID: 34819501
PMCID: PMC8613194
Date of Paper: 24/11/2021
Division: Cell BiologyLlácer J. L., Hussain T., Dong J., Villamayor L., Gordiyenko Y., Hinnebusch A. G.
Large-scale movement of eIF3 domains during translation initiation modulate start codon selection
Nucleic Acids Research 49(20):11491-11511DOI: 10.1093/nar/gkab908
PMID: 34648019
PMCID: PMC8599844
Date of Paper: 18/11/2021
Division: Structural StudiesHumphreys I. R., Pei J., Baek M., Krishnakumar A., Anishchenko I., Ovchinnikov S., Zhang J., Ness T. J., Banjade S., Bagde S. R., Stancheva V. G., Li X. H., Liu K., Zheng Z., Barrero D. J., Roy U., Kuper J., Fernández I. S., Szakal B., Branzei D., Rizo J., Kisker C., Greene E. C., Biggins S., Keeney S., Miller E. A., Fromme J. C., Hendrickson T. L., Cong Q., Baker D.
Computed structures of core eukaryotic protein complexes
Science 374(6573):eabm4805. 11 November 2021DOI: 10.1126/science.abm4805
PMID: 34762488
PMCID: PMC7612107
Date of Paper: 11/11/2021
Division: Cell BiologyEschbach C., Fushiki A., Winding M., Afonso B., Andrade I. V., Cocanougher B. T., Eichler K., Gepner R., Si G., Valdes-Aleman J., Fetter R. D., Gershow M., Jefferis G. S., Samuel A. D., Truman J. W., Cardona A., Zlatic M.
Circuits for integrating learned and innate valences in the insect brain
Elife 10:e62567. 10 November 2021DOI: 10.7554/elife.62567
PMID: 34755599
PMCID: PMC8616581
Date of Paper: 10/11/2021
Division: NeurobiologyMalvezzi F., Stubbs C. J., Jowitt T. A., Dale I. L., Guo X., DeGnore J. P., Degliesposti G., Skehel J. M., Bannister A. J., McAlister M. S.
Phosphorylation-dependent BRD4 dimerization and implications for therapeutic inhibition of BET family proteins
Communications Biology 4(1):1273. 9 November 2021DOI: 10.1038/s42003-021-02750-6
PMID: 34754068
PMCID: PMC8578508
Date of Paper: 09/11/2021
Division: Cell BiologyMlcochova P., et al (Including Papa G., Albecka A., James L. C.)
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion
Nature 599(7883):114-119. 4 November 2021DOI: 10.1038/s41586-021-03944-y
PMID: 34488225
PMCID: PMC8566220
Date of Paper: 04/11/2021
Division: Protein & Nucleic Acid ChemistryPogodalla N,. Kranenburg H,. Rey S., Rodrigues S., Cardona A., Klämbt C.
Drosophila ßHeavy-Spectrin is required in polarized ensheathing glia that form a diffusion-barrier around the neuropil
Nature Communications 12(1):6357. 4 November 2021DOI: 10.1038/s41467-021-26462-x
PMID: 34737284
PMCID: PMC8569210
Date of Paper: 04/11/2021
Division: NeurobiologyMonkley S., Overed-Sayer C., Parfrey H., Rassl D., Crowther D., Escudero-Ibarz L., Davis N., Carruthers A., Berks R., Coetzee M., Kolosionek E., Karlsson M., Griffin L. R., Clausen M., Belfield G., Hogaboam C. M., Murray L. A.
Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF
Scientific Reports 11(1):21584. 3 November 2021DOI: 10.1038/s41598-021-00769-7
PMID: 34732748
PMCID: PMC8566588
Date of Paper: 03/11/2021
Division: Protein & Nucleic Acid ChemistrySanchez-Bailon M. P., Choi S. Y., Dufficy E. R., Sharma K., McNee G. S., Gunnell E., Chiang K., Sahay D., Maslen S., Stewart G. S., Skehel J. M., Dreveny I., Davies C. C.
Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair
Nature Communications 12(1):6313. 2 November 2021DOI: 10.1038/s41467-021-26413-6
PMID: 34728620
PMCID: PMC8564520
Date of Paper: 02/11/2021
Division: Cell BiologyDunkelmann D. L., Oehm S. B., Beattie A. T., Chin J. W.
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design
Nature Chemistry 13(11):1110-1117. November 2021DOI: 10.1038/s41557-021-00764-5
PMID: 34426682
PMCID:
Date of Paper: 01/11/2021
Division: Protein & Nucleic Acid ChemistryCoscia F., Löwe J.
Cryo-EM structure of the full-length Lon protease from Thermus thermophilus
FEBS Letters 595(21):2691-2700. November 2021DOI: 10.1002/1873-3468.14199
PMID: 34591981
PMCID:
Date of Paper: 01/11/2021
Division: Structural StudiesKumar A., Yu C. W. H., Rodríguez-Molina J. B., Li X. H., Freund S. M. V., Passmore L. A.
Dynamics in Fip1 regulate eukaryotic mRNA 3' end processing
Genes & Development 35(21-22):1510-1526. 1 November 2021DOI: 10.1101/gad.348671.121
PMID: 34593603
PMCID: PMC8559680
Date of Paper: 01/11/2021
Division: Structural Studies, Cell Biology