The connectome of an animal is the comprehensive map, or wiring diagram, of all the neural connections in the brain. However, an important challenge is how to make sense of this information. The nematode worm Caenorhabditis elegans, still the only animal for which the entire connectome has been described, illustrates the problem. Although it has […]
Network control principles predict neuron function in the C. elegans connectome
The birth of the cool
Super cool microscopy wins the 2017 Nobel prize in chemistry: includes interview with LMB’s Richard Henderson. More…
Xiaochen Bai – first atomic structure from UTSW’s Cryo-EM facility
UT Southwestern Medical Center researchers have published a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans. The work marks the first such structure determined using the university’s $17 million electron cryo-microscopy (cryo-EM) facility that opened last year. Xiaochen Bai, an Assistant Professor […]
Electron cryo-microscopy wins chemistry Nobel
Jacques Dubochet, Joachim Frank and Richard Henderson were awarded the prize on 4 October for their work in developing electron cryo-microscopy (cryo-EM), a technique that fires beams of electrons at proteins that have been frozen in solution, to deduce the biomolecules’ structure. More…
Richard Henderson shares 2017 Nobel Prize in Chemistry
The Nobel prize in chemistry has been awarded to three scientists, Jacques Dubochet, Joachim Frank and the LMB’s Richard Henderson, for developing a technique to produce images of the molecules of life frozen in time. The technique, called cryo-electron microscopy, allowed biomolecules to be visualised in their natural configuration for the first time, triggering a “revolution in […]
Richard Henderson wins 2017 Nobel Prize for Chemistry
Richard Henderson from the LMB’s Structural Studies Division has been awarded the 2017 Nobel Prize for Chemistry. Richard shares the honour jointly with Jacques Dubochet and Joachim Frank “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution”. Speaking after today’s announcement, Richard responded “I am delighted for everybody in the field that […]