Simon Bullock discusses his research into intracellular trafficking of RNA, and talks about the importance of science outreach in inspiring the next generation of young scientists. More…
Exploring the incredible transport system inside our cells
Sharp focus on Alzheimer’s may help target drugs
Abnormal deposits that build up in the brain during Alzheimer’s have been pictured in unprecedented detail in research led by Sjors Scheres and Michel Goedert. More…
A new tool to study neural networks
Neural networks, circuits of neurons, are emerging as the fundamental computational unit of the brain and it is becoming progressively clearer that neural network dysfunction is at the core of a number of psychiatric and neurodegenerative disorders. Yet our ability to target and study specific neural networks remains limited. Until now Rabies virus, which can […]
Cell lineage tracing – from pioneer John Sulston, to today’s ground-breaking research
John Sulston, Nobel prize winner in 2002, determined the cell lineage of the nematode worm C. elegans. Using new cutting-edge technologies, researchers across the world are now aiming to trace cell lineages in a variety of other organisms. More…
G-protein coupled receptors as drug targets: Heptares Therapeutics celebrates its tenth anniversary
Chris Tate – co-founder of Heptares Therapeutics, a company established to commercialise research from the LMB – discusses his work on G-protein coupled receptors. More…
First atomic structures of Tau filaments from Alzheimer’s disease brain
Alzheimer’s disease, the most common neurodegenerative disease, is characterised by the formation of filamentous Tau protein inside nerve cells and amyloid-beta peptides outside cells. Despite more than three decades of research into Tau filaments from a range of different neurodegenerative diseases, atomic structures were still lacking. Now, research by the groups of Sjors Scheres in […]