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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > A new view of the spliceosome

A new view of the spliceosome

A new view of the spliceosome

Published on 26 May, 2017

Kiyoshi Nagai’s group capture important state of cellular machine responsible for making humans more complex than worms. More…

Dynamic structure of human DNA repair enzyme, ATM, revealed

Published on 11 May, 2017

The DNA in cells is constantly damaged by both internal activities of the cell and by external factors such as ionising radiation. In order to function correctly, this damage must be repaired, or if it cannot be repaired, the cell must be killed to prevent development of diseases such as cancer. The large protein kinase, […]

The key to GPCR-G protein selectivity

Published on 11 May, 2017

G protein-coupled receptors (GPCRs) form the largest family of membrane-protein receptors and drug targets. With over 800 different family members in humans, GPCRs regulate diverse intracellular signalling cascades in different cell types, tissues and organ systems. Whilst GPCRs sense a plethora of environmental stimuli, the appropriate cellular response is primarily triggered by binding to four […]

Mo Moffateh’s winning science image

Published on 8 May, 2017

Mo Moffateh’s image of beautifully repeated segments of Drosophila melanogaster embryonic nervous system, picked as joint third in British Society for Cell Biology’s 2017 winning images. More…

Anne Bertolotti elected Fellow of the UK Academy of Medical Sciences

Published on 8 May, 2017

Anne Bertolotti, group leader in the LMB’s Neurobiology Division, has been elected a Fellow of the UK Academy of Medical Sciences for her contribution to understanding protein quality control systems and their therapeutic manipulations. The Academy represents the diverse spectrum of medical sciences – from basic research through clinical application to healthcare delivery. Their mission […]

Three LMB scientists elected Fellows of the Royal Society

Published on 5 May, 2017

Andrew McKenzie, John Sutherland and Roger Williams, all Group Leaders in the LMB’s PNAC Division, have been elected Fellows of the Royal Society.  The Royal Society is a Fellowship of the world’s most eminent scientists and is the oldest scientific academy in continuous existence.  It seeks to promote excellence in science, electing up to 52 […]

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