Professor Thomas Südhof will give the 2017 Milstein Lecture on Thursday 9th February 2017 at 4pm in the LMB’s Max Perutz Lecture Theatre. The lecture, entitled “Molecular Mechanisms of Synaptic Transmission”, is open to anyone in the local area who is interested in attending. Thomas is Professor in the Department of Molecular and Cellular Physiology […]
2017 Milstein Lecture to be given by Thomas Südhof
Uncovering the molecular basis of triage during protein synthesis
Every minute, cells make millions of new proteins which must be transported to the correct location, folded, modified and assembled with other proteins in order to function properly. Failure at any of these maturation steps can reduce protein function and lead to the accumulation of aberrant protein intermediates, resulting in disease. To mitigate this, protein […]
IL-17, a regulator of the immune system, impacts behaviour
The state of the immune system has effects on brain function, but despite suggestions that immunoregulators can affect people’s mood and behaviour, we are only beginning to understand how these two major body systems interact. The contributions of a neuron to circuit activity and behaviour depend on its responsiveness to upstream inputs, and its ability […]
Antibodies co-opt anti-microbial response to clear intraneuronal tau
Leo James and Michel Goedert, group leaders at the LMB, recently published work in PNAS providing an explanation for how therapeutic antibodies eliminate pathogenic forms of tau protein. Here, Alzforum explore the background, results and implications of this study. More…
Dementia – how close are we to having effective treatments?
Cambridge Neuroscience, of which the LMB is a part, plays a key role in coordinating dementia research across the large and diverse community of neuroscientists in Cambridge, helping scientists and clinicians work together. The organisation has produced a new film describing some of the progress now being made against this devastating disease, including commentary from […]
LMB welcomes new group leaders: John Briggs and Julian Gough
The LMB is delighted to announce the recent arrival of two new group leaders in the LMB’s Structural Studies Division: John Briggs and Julian Gough. John Briggs John’s group studies the structures of cellular trafficking vesicles and of enveloped viruses, aiming to uncover the mechanisms that underlie their assembly and disassembly. Cellular vesicles are used […]