DNA damage represents a constant threat to the integrity of genomic information in cells and is closely linked to the origins of cancer. DNA single-strand breaks (SSBs) are the most frequent type of damage with thousands of such lesions from different sources occurring in each cell every day. Despite many advances in understanding the mechanistic […]
Detecting and signalling DNA single-strand breaks: understanding the mechanisms of DNA damage recognition
“Gifted and Talented” sixth-formers visit LMB for degree-level practicals
26 AS-level students on an intensive week of “Biology and Genetics for Gifted and Talented students” recently visited the LMB for a day of practical work. The residential course was run at Villiers Park Educational Trust, Foxton, Cambridgeshire and the students were nominated from schools all over the UK. The aim of the week was […]
Molecular clocks control mutation rate in human cells
New research suggests that cancer and ageing could be predetermined by the speed of molecular clocks. This collaborative project includes work by LMB group leader Julian Sale. More…
DNA sculpture from CRUK Art Trail finds home in Francis Crick’s former Laboratory
During the summer of 2015 Cancer Research UK launched a DNA inspired art trail across London with a series of 21 DNA double helix sculptures. They invited some of the biggest names in the world of art and design to create unique pieces by asking them ‘what’s in your DNA?’ One of these designs, ‘What […]
Researchers grow brain parts to study development, disease
Dozens of labs are growing lumps of human brain tissue – brain organoids – for study, including LMB’s Madeline Lancaster. Scientists say the technology holds great potential for studying the roots of diseases like autism and schizophrenia, testing possible treatments and tackling basic questions about evolution. More…
The Worm Wide Web – Max Perutz Science Writing Award
An article written by Barry Bentley, a PhD student in the LMB’s Neurobiology Division, telling the story of how the tiny nematode worm continues to make a big impact on medical research, has been awarded a commendation prize in the Max Perutz Science Writing Award 2015. Barry’s article, ‘The Worm Wide Web: mapping the networks […]