Steve West will give the 2012 Max Perutz lecture on Thursday 13 September at 4.15pm in the Max Perutz Lecture Theatre at the LMB. The lecture, entitled “Defective DNA strand break repair, genome instability and cancer” is open to all interested in attending. Steve West is known for pioneering studies on homologous recombination, and for defining the […]
2012 Max Perutz lecture to be given by Steve West
New insight into common mutations in human cancers
One of the most commonly mutated genes in human cancers is the lipid kinase PIK3CA (phosphoinositide 3-kinase alpha). Mutations can activate this enzyme, resulting in proliferation of tumour cells and resistance to programmed cell death or apoptosis. By applying the powerful technique of hydrogen/deuterium exchange mass spectrometry to map this complex system, a team of […]
Alcohol by-product destroys blood stem cells
Scientists at the Medical Research Council (MRC) Laboratory of Molecular Biology have found that stem cells in the body’s ‘blood cell factory’ – the bone marrow – are extremely sensitive to the main breakdown product of alcohol, which causes irreversible damage to their DNA… This article is no longer available from the source website: Cambridge […]
Students embrace the art of science
Young artists from across Cambridgeshire have combined science with art for an annual creative challenge. Organised by Cambridge’s prestigious Medical Research Council Laboratory of Molecular Biology (MRC-LMB), the Imagining the Brain project is an open exhibition designed to encourage students across the county to communicate scientific concepts through art… This article is no longer available […]
Alcohol by-product destroys blood stem cells
New research shows that acetaldehyde, the breakdown product generated when the body removes alcohol, causes irreversible damage to the DNA of stem cells in the body’s ‘blood cell factory’ – the bone marrow. The research, published in Nature, was carried out by a team of scientists led by KJ Patel in the LMB’s PNAC Division. […]
Synthetic ‘Upgrade’ for fruit fly’s DNA
The genetic code of the fruit fly Drosophila has been hacked into, allowing it to make proteins with properties that don’t exist in the natural world. […] Jason Chin at the Medical Research Council Laboratory of Molecular Biology in Cambridge… More…