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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > New pathway for cells to detect bacterial infection

New pathway for cells to detect bacterial infection

New pathway for cells to detect bacterial infection

Published on 6 July, 2023

Felix Randow’s group, in the LMB’s PNAC Division, have discovered TECPR1 as a novel E3 ligase, which, when sensing sphingomyelin on damaged membranes, conjugates the ubiquitin-like autophagy protein LC3 to those membranes.

Katja Röper elected to EMBO membership

Published on 4 July, 2023

EMBO names Katja Röper, of LMB’s Cell Biology Division, amongst its newly elected members.

Sarah Cumbers appointed chief executive of Royal Statistical Society

Published on 27 June, 2023

LMB 1997-2001, PhD Student, PNAC Sarah Cumbers has been announced as the new chief executive of the Royal Statistical Society (RSS), a professional body founded in 1834 dedicated to the promotion of the relevance of statistics and application for the public good. She is due to begin her role in September 2023. More…

Pore-forming protein perforin-2 is critical to immune response by dendritic cells

Published on 23 June, 2023

Patrycja Kozik’s group, in the LMB’s PNAC Division, find that the pore-forming protein perforin-2 is an effector of antigen escape in dendritic cells – a critical component to T cell mediated immune responses.

Stephen Wallace wins Norman Heatley Award from Royal Society of Chemistry

Published on 21 June, 2023

LMB 2012-2013, Career Development Fellow, PNAC The Royal Society of Chemistry has announced Stephen Wallace as the 2023 recipient of the Norman Heatley Award. Here, he speaks to the society, covering his career motivations, challenges he’s faced and advice for young chemists. More…

Antiviral Bicycles are effective against SARS-CoV-2

Published on 16 June, 2023

A collaborative study including researchers in Leo James’ group in the LMB’s PNAC Division and Bicycle Therapeutics has developed a new class of antivirals which can be combined together like building blocks to effectively immobilise COVID-19’s Spike protein and block infection.

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