Lori Passmore’s group in the LMB’s Structural Studies Division have identified the molecular mechanism by which the FANCD2-FANCI protein complex, which acts as a travelling DNA clamp, is able to identify sites of DNA strand damage and mark them for repair.
Insight on Research
Motion detector in the brain translates visual information into movement
Marco Tripodi’s group, in the LMB’s Neurobiology Division, reveals how visual information is progressively channelled to motor neurons.
Transcription factor Mef2d is crucial to the function of type-2 innate lymphoid cells during allergic responses
Andrew McKenzie’s group, in the LMB’s PNAC Division, have applied a new screening system and synthetic Boolean logic gate circuits to offer unprecedented insights into the molecular regulation of type-2 innate lymphoid cells, a key contributor to allergic responses.
In-cell structure elucidation reveals a functional significance of microbial S-layers in critical global geochemical cycles
Tanmay Bharat’s group, in the LMB’s Structural Studies Division, reveals the surface layer structure of the archaeon Nitrosopumilus maritimus, crucial to the global nitrogen cycle.
First map of the neurotransmitters used in the fruit fly brain
Greg Jefferis’ group in the LMB’s Neurobiology Division, in collaboration with scientists at the Janelia Research Campus, have predicted the sign of each synapsis in the fruit fly brain.
ModelAngelo software expands cryo-EM toolkit with faster atomic model building and identification of novel proteins
Kiarash Jamali, a Ph.D. student in Sjors Scheres’ group in the LMB’s Structural Studies Division, has designed a new machine learning software capable of fast, accurate model building at atomic levels and identification of new proteins beyond previous capabilities.