The image for day 231 of #LMB365 shows a sample of baker’s yeast labeled with fluorescent dyes. Three dyes (red, green and blue) create seven different colour combinations. These multi-coloured images are used as part of a method developed by John Briggs’ group in collaboration with colleagues from the Weizmann Institute of Science to perform multiple electron microscopy experiments in parallel. Yeast cells from different experiments get a unique colour-code. They are then pooled together in one sample for electron microscopy. By reading the colour-code, the experimenter can later work out which cell came from which experiment. http://jcb.rupress.org/content/218/8/2797
LMB 365 – Day 231
LMB 365 – Day 230
This photo for day 230 of #LMB365 shows the newly installed heat exchanger for the new Scientific Computing server room. The primary chilled water system in the building is at 4C, and this heat exchanger ensures that the water cooling used for the computer racks is raised to 14C to prevent any condensation forming in the server room
LMB 365 – Day 229
Day 229 of #LMB365 shows a member of staff taking advantage of Wellness Wednesday at the LMB with a non-subsidized seated massage treatment. This uses a combination of massage and acupressure techniques to the back, neck, shoulders, arms, hands and scalp to relieve tension and reduce stress. No need to undress and no oils used, so you can go straight back to work feeling refreshed and revitalised. Blissssss…
LMB 365 – Day 228
Day 228 of #LMB365 was provided by Rosemary Keeble in Lalita Ramakrishnan’s group. They use zebrafish as a model organism to study human diseases such as tuberculosis. It is important to ensure the welfare of the fish and bacteria-free egg water containing the antifungal agent methylene blue is used to incubate embryos to ensure survival pre-hatching. This image shows 1 litre of egg water in a glass bottle viewed from above.
Future scientists and science leaders visit the LMB
The LMB recently hosted visits from two diverse groups of students; one that was attending the 2019 London International Youth Science Forum (LIYSF) and the other from the 2019 cohort of Schmidt Science Fellows. London International Youth Science Forum visit LIYSF is a two-week residential course for students aged 16-21 who have a keen interest […]
LMB 365 – Day 227
It is generally thought that abnormal proteins aggregate, the aggregates get ubiquitinated, and this leads to their degradation by autophagy or the proteasome. Hugh Pelham’s group in Cell Biology has been working on ubiquitination of protein condensates by Nedd4 ubiquitin ligases. These images for day 227 of #LMB365 show that artificial protein condensates (green, left) […]