The first weekend of the 2017 Cambridge Science Festival saw over 3000 visitors attend the ‘Hands-on at the Guildhall’ event, where the LMB’s ‘See Your Cells’ activity proved hugely popular. Mathias Pasche and his team of 25 enthusiastic volunteers gave visitors the unique opportunity to see their own cells, by simply taking a cheek swab, […]
Hundreds of children and adults enjoy the LMB’s ‘See Your Cells’ activity at the Cambridge Science Festival
LMB PhD student takes her research to Parliament
Cara Ellison, a PhD student in Felix Randow’s group in the LMB’s PNAC Division, attended Parliament to present her research to a range of politicians and a panel of expert judges, as part of STEM for BRITAIN on Monday 13 March. Cara was shortlisted from hundreds of applicants to appear in Parliament. She presented a […]
Visualising the genome: Cambridge scientists create first 3D structures of active DNA
Tim Stevens, in collaboration with scientists from the University of Cambridge, has determined the first 3D structures of intact mammalian genomes from individual cells, showing how the DNA from all the chromosomes intricately folds to fit together inside the cell nuclei. More…
Integral component of the Wnt enhancesome identified
The Wnt signalling pathway is an ancient cell communication pathway that has important roles in development and cancer. Wnt signals elicit context-dependent transcriptional responses by stabilising a cytoplasmic effector called beta-catenin. This controls the embryonic development of tissues and organs in all animals, from the most primitive ones all the way to humans. In addition, […]
First complete 3D genome structure from individual mammalian cells
DNA in the nucleus is arranged into nucleosomes to produce an 11nm fibre which then intricately folds into high order assemblies. This nuclear organisation – the 3D arrangement of the genome within the nucleus – is critically linked to nuclear processes. Previously it has only been possible to analyse genome organisation across populations of cells. […]
Julian Gough discusses the wonders of the SUPERFAMILY database
Julian Gough is interviewed by the Huffington Post and discusses SUPERFAMILY, his database of structural and functional annotations for proteins and genomes, a public resource which scientists around the world can use freely in their research. More…