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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Redirecting the rules of attraction in fruit flies

Redirecting the rules of attraction in fruit flies

Redirecting the rules of attraction in fruit flies

Published on 16 January, 2014

Researchers at the LMB have discovered a biological switch that determines which part of the fruit fly’s brain responds to pheromones, depending on whether it is male or female. This is the first study to show specific changes in nerve cell wiring that reroutes information differently in male and female brains. More…

Fred Sanger Obituary

Published on 15 January, 2014

Nature carries an obituary of the late Dr Fred Sanger, double Nobel Prize winner for amino acid and DNA sequencing. The article, written by Professor Sir John Walker, who worked with Sanger at the LMB, describes him as “happiest at the laboratory bench, where he worked tirelessly and single-mindedly”. More…

Coupling of transcription termination and mRNA processing

Published on 13 January, 2014

Work carried out by Lori Passmore’s group in the LMB’s Structural Studies Division, in collaboration with Patrick Cramer’s group in Munich, has revealed how transcription termination and mRNA processing by Cleavage and Polyadenylation Factor (CPF) are coupled via dephosphorylation of the C-terminal domain of RNA Polymerase II by CPF. Genes code for proteins – the […]

The 12 days of the MRC Centenary

Published on 20 December, 2013

2013 has been a big year for the MRC, marking 100 years since our founding committee met for the first time.  Throughout the year we celebrated the past, present and future of the MRC.  Highlights included the opening of the new LMB building. More…

A switch in the brain

Published on 20 December, 2013

Research from Greg Jefferis’s group in the LMB’s Neurobiology Division has uncovered a biological switch that determines which part of the fruit fly’s brain responds to pheromones, depending on whether the fruit fly is male or female. Previous studies have identified differences in brain structure between the sexes but this study, published in Cell, is […]

KJ Patel receives Fanconi Anemia Research Fund Award of Merit

Published on 18 December, 2013

KJ Patel, from the LMB’s PNAC Division, has been awarded the Award of Merit for his ‘revolutionary work on aldehyde toxicity in Fanconi anemia hematopoietic cells’ by the Board of Directors of the Fanconi Anemia Research Fund. Fanconi Anemia (FA) is a rare, cancer-predisposing disorder affecting about 150 or more families in the UK (the […]

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