Researchers at the LMB have discovered a biological switch that determines which part of the fruit fly’s brain responds to pheromones, depending on whether it is male or female. This is the first study to show specific changes in nerve cell wiring that reroutes information differently in male and female brains. More…
Redirecting the rules of attraction in fruit flies
Fred Sanger Obituary
Nature carries an obituary of the late Dr Fred Sanger, double Nobel Prize winner for amino acid and DNA sequencing. The article, written by Professor Sir John Walker, who worked with Sanger at the LMB, describes him as “happiest at the laboratory bench, where he worked tirelessly and single-mindedly”. More…
Coupling of transcription termination and mRNA processing
Work carried out by Lori Passmore’s group in the LMB’s Structural Studies Division, in collaboration with Patrick Cramer’s group in Munich, has revealed how transcription termination and mRNA processing by Cleavage and Polyadenylation Factor (CPF) are coupled via dephosphorylation of the C-terminal domain of RNA Polymerase II by CPF. Genes code for proteins – the […]
The 12 days of the MRC Centenary
2013 has been a big year for the MRC, marking 100 years since our founding committee met for the first time. Throughout the year we celebrated the past, present and future of the MRC. Highlights included the opening of the new LMB building. More…
A switch in the brain
Research from Greg Jefferis’s group in the LMB’s Neurobiology Division has uncovered a biological switch that determines which part of the fruit fly’s brain responds to pheromones, depending on whether the fruit fly is male or female. Previous studies have identified differences in brain structure between the sexes but this study, published in Cell, is […]
KJ Patel receives Fanconi Anemia Research Fund Award of Merit
KJ Patel, from the LMB’s PNAC Division, has been awarded the Award of Merit for his ‘revolutionary work on aldehyde toxicity in Fanconi anemia hematopoietic cells’ by the Board of Directors of the Fanconi Anemia Research Fund. Fanconi Anemia (FA) is a rare, cancer-predisposing disorder affecting about 150 or more families in the UK (the […]