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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Coupling of transcription termination and mRNA processing

Coupling of transcription termination and mRNA processing

Coupling of transcription termination and mRNA processing

Published on 13 January, 2014

Work carried out by Lori Passmore’s group in the LMB’s Structural Studies Division, in collaboration with Patrick Cramer’s group in Munich, has revealed how transcription termination and mRNA processing by Cleavage and Polyadenylation Factor (CPF) are coupled via dephosphorylation of the C-terminal domain of RNA Polymerase II by CPF. Genes code for proteins – the […]

The 12 days of the MRC Centenary

Published on 20 December, 2013

2013 has been a big year for the MRC, marking 100 years since our founding committee met for the first time.  Throughout the year we celebrated the past, present and future of the MRC.  Highlights included the opening of the new LMB building. More…

A switch in the brain

Published on 20 December, 2013

Research from Greg Jefferis’s group in the LMB’s Neurobiology Division has uncovered a biological switch that determines which part of the fruit fly’s brain responds to pheromones, depending on whether the fruit fly is male or female. Previous studies have identified differences in brain structure between the sexes but this study, published in Cell, is […]

KJ Patel receives Fanconi Anemia Research Fund Award of Merit

Published on 18 December, 2013

KJ Patel, from the LMB’s PNAC Division, has been awarded the Award of Merit for his ‘revolutionary work on aldehyde toxicity in Fanconi anemia hematopoietic cells’ by the Board of Directors of the Fanconi Anemia Research Fund. Fanconi Anemia (FA) is a rare, cancer-predisposing disorder affecting about 150 or more families in the UK (the […]

Winners of the Imagining the Brain competition announced

Published on 16 December, 2013

The winners of the 2013 competition on “The Changing Brain” were recently awarded their prizes. This article is no longer available from the source website: Cambridge News 16 December 2013

Profiles of 2013 Nobel Laureates in Chemistry

Published on 6 December, 2013

You can read the Nobel Prize Web site for the best description of the science behind the 2013 Nobel Prize in Chemistry. However, let me tell you what the beginnings of the science and its immediate impact were really like – a personal account from a close by-stander (Alan Fersht). More…(Subscription required)

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