“Interested in overcoming the PCR inhibitors often present in complex environmental samples, Phil Holliger and colleagues decided the best solution to the problem was to re-engineer a better polymerase – an ‘evolved’ polymerase that offered resistance to the environmental inhibitors.” This article is no longer available from the source website: Biotechniques 2 February 2012
Evolution at the lab bench
Focus on Jason Chin
“EMBO Member Jason Chin, MRC Laboratory of Molecular Biology, talks about reprogramming the genetic code and re-engineering ribosomes and the possibility of building a parallel biological system. He also talks about in-vivo experiments in biochemistry, gives advice to young researchers and how he benefitted from being an EMBO Young Investigator.” More…
£1500 Raised for Acorn House Charity
Hugh Pelham, Director of the LMB, recently presented Joy Worship, Manager of Acorn House, The Sick Children’s Trust, with a cheque for £1496.30, which was raised at the LMB’s annual Christmas Charity Raffle. Joy was delighted with the gift and said that the contribution would go towards the £68,000 annual running costs of Acorn House, […]
The sweet way of detecting bacterial invasion in cells
Felix Randow’s group in the LMB’s PNAC Division has identified Galectin-8 as a novel danger receptor and factor of the cellular machinery that protects human cells against bacterial invasion. Galectin 8, a sugar-binding protein in the cytosol, was discovered to be a key component in limiting the growth of Salmonella and to participate in the […]
Novel Mechanism for Regulating Inflammation and Cancer Discovered
Matthew Freeman’s group in the LMB’s Cell Biology Division have discovered a novel protein, iRhom2, that plays a central role in the signalling pathways that regulate inflammation and cancer. The cytokine protein, TNF, is the primary trigger of inflammation in humans. To function, active TNF must be shed from cells by the protease TACE. TACE […]
Sean Munro Elected as AAAS Fellow
Sean Munro, group leader in the LMB’s Cell Biology Division, has been elected as a Fellow of The American Association for the Advancement of Science (AAAS). Election as a Fellow of AAAS is an honour bestowed upon members by their peers. Fellows are recognized for meritorious efforts to advance science or its applications. Founded in […]