Sir Gregory Winter (Master of Trinity College, University of Cambridge and the former Deputy Director of the LMB) was one of the two outstanding Medical Research Council (MRC) research scientists to be awarded the prestigious MRC Millennium medal. The medals were awarded at a ceremony at the House of Commons on 27 February, which was […]
MRC Millennium medal recognises LMB’s exceptional research
LMB’s Felix Randow in discussion with Annalisa M. VanHook
LMB’s Felix Randow in discussion with Annalisa M. VanHook from the journal Science about the process of autophagy. More…
A Glimpse Inside the Control Centers of Cell Communication
Scientists from the LMB’s Structural Studies Division, led by M. Madan Babu in collaboration with Chris Tate (LMB) and researchers from the Paul Scherrer Institut, have detected characteristic constructional features in a family of sensors that process signals in the human body and control physiological processes. More…
The story of monoclonal antibodies – online
A new online exhibition, sponsored by the MRC as part of its centenary, explores where monoclonal antibodies came from and how they began to be applied to improve our understanding of disease and to advance treatment. ‘A healthcare revolution in the making: The story of César Milstein and monoclonal antibodies’, sponsored by the Medical Research […]
Uncovering molecular signatures of G-protein-coupled receptors
G-protein-coupled receptors (GPCRs) are a family of cell-surface proteins that are vital for various physiological functions including vision, smell, taste, and behavior. They are also the pharmacological targets of ~30% of prescribed drugs. For example, beta-blocker drugs prescribed for cardiac ailments target the β-adrenoreceptors − known GPCRs. The importance of GPCR biology was emphasised by […]
Ribosome structure determined to near-atomic resolution by cryo-EM
Determining the structure of proteins and other biomolecules at the atomic level is central to understanding many aspects of biology. X-ray crystallography is the best known technique for structural biology but, as its name suggests, it only works with samples that can be crystallized. Electron cryo-microscopy (cryo-EM) can be used to determine atomic structures of […]