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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > How bacteria ensure stalled ribosomes are rescued

How bacteria ensure stalled ribosomes are rescued

How bacteria ensure stalled ribosomes are rescued

Published on 28 March, 2012

Venki Ramakrishnan’s group, from the LMB’s Structural Studies Division, has provided structural evidence for how bacterial transfer-messenger RNA (tmRNA) rescues stalled ribosomes at the end of prematurely truncated or defective messenger RNAs and targets incompletely synthesised proteins for degradation. tmRNA (also known as 10S RNA) combines properties of both transfer RNA (tRNA) and messenger RNA […]

LMB has been awarded £49m to study the human brain

Published on 27 March, 2012

“The LMB will receive nearly £170m core funding support from the Medical Research Council over the next five years to pursue its mission of understanding biological processes at the molecular level, including £49m for examining the biology of the brain. The award will also fund an increased focus on the processes affecting cellular damage and […]

ScienceOnline2012 – interview with Josh Witten

Published on 22 March, 2012

“Every year I ask some of the attendees of the ScienceOnline conferences to tell me (and my readers) more about themselves, their careers, current projects and their views on the use of the Web in science, science education or science communication. Today my guest is Josh Witten (blog, Twitter) from the Laboratory of Molecular Biology.” […]

‘See your cells!’ at Cambridge Science Festival

Published on 16 March, 2012

On Saturday 17th and Sunday 18th March, LMB scientists, led by Simon Bullock and Isabel Torres, provided fun, hands-on activities at the Cambridge Science Festival encouraging children to learn about cells and microscopy. Children visiting the ‘See Your Cells!’ stand in the Biology Zone donned lab coats and used a microscope to see their own […]

The invention of the microscope

Published on 15 March, 2012

“LMB’s Brad Amos helps explains the importance of the microscope. Also includes some images from LMB.” More…

Link between shape shifting protein and HIV resistance

Published on 12 March, 2012

A group of collaborative researchers, led by Leo James’ group in the LMB’s PNAC Division, have discovered evidence that helps to explain why primates are more resistant to HIV than humans are. Rhesus macaques are protected against HIV by a protein, Rhesus TRIMCyp (RhTC), which targets HIV inside cells thereby preventing infection. However, how RhTC […]

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