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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Keeping protein subunits in check via assembly quality control 

Keeping protein subunits in check via assembly quality control 

Keeping protein subunits in check via assembly quality control 

Published on 21 July, 2023

Cells eliminate “orphan” proteins that have failed to assemble into the molecular machines within which they normally function. Manu Hegde’s group have now elucidated the mechanism by which one type of orphan is selectively recognised and tagged for destruction.

LMB alumnae return to share their career stories at the fourteenth LMB-Cambridge AWiSE event

Published on 19 July, 2023

Anne Cooke, Stephanie Pilkington and Hayley Sharpe returned to the LMB as speakers at this year’s ‘What Next for Your Career’ event, highlighting the importance of a good work-life balance, finding the right mentors, building networks and staying in touch with old colleagues as powerful tools for future opportunities.

Great British Railway Journeys visits LMB to learn about the significance of the discovery of the structure of DNA

Published on 17 July, 2023

At the end of his Brandon to Cambridge railway journey, Michael Portillo visits the LMB to talk to Venki Ramakrishnan about the significance of the discovery of the double helix structure of DNA by James Watson and Francis Crick. Venki shares how the team solved this puzzle by combining data from various sources, including X-Ray […]

New pathway for cells to detect bacterial infection

Published on 6 July, 2023

Felix Randow’s group, in the LMB’s PNAC Division, have discovered TECPR1 as a novel E3 ligase, which, when sensing sphingomyelin on damaged membranes, conjugates the ubiquitin-like autophagy protein LC3 to those membranes.

Katja Röper elected to EMBO membership

Published on 4 July, 2023

EMBO names Katja Röper, of LMB’s Cell Biology Division, amongst its newly elected members.

Sarah Cumbers appointed chief executive of Royal Statistical Society

Published on 27 June, 2023

LMB 1997-2001, PhD Student, PNAC Sarah Cumbers has been announced as the new chief executive of the Royal Statistical Society (RSS), a professional body founded in 1834 dedicated to the promotion of the relevance of statistics and application for the public good. She is due to begin her role in September 2023. More…

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