The LMB is delighted to announce the recent arrival of two new group leaders in the LMB’s Cell Biology Division: Madeline Lancaster and Liz Miller. Madeline Lancaster Madeline’s research is in the area of human brain development. Human brain development exhibits a number of unique characteristics, such as dramatic size expansion, unique cell types, and […]
LMB welcomes new group leaders: Madeline Lancaster and Liz Miller
Stop codons: a decoding puzzle decoded
New research from the LMB’s Cell Biology and Structural Studies Divisions has answered a long-standing problem in molecular biology: how does the ribosome decode the signals to stop protein synthesis? In cells, all proteins are produced by ribosomes that ‘read’ messenger RNA (mRNA) one codon, or three nucleotides, at a time. Protein translation terminates when […]
Staff show their creative side at the LMB Art Exhibition
Nearly 30 LMB staff have shown off their creativity at the annual LMB Art Exhibition, an opportunity for staff to showcase their varied artistic talents. The display was organised for the 4th year by Brian Saltmarsh, from the LMB’s Laboratory Services Section. The display, in the atrium of the building, featured work across a wide […]
New body clock regulatory pathway discovered
In a long-standing collaborative effort, groups at MRC Harwell, the LMB, and the University of Oxford have discovered a new genetic mechanism in the circadian body clock that could have important implications for research in mental health and psychiatric disease. Biological clocks run in all our cells, controlling the timing of a number of crucial […]
Madan Babu Mohan awarded the Royal Society Francis Crick Medal and Lecture 2016
Madan Babu Mohan, group leader in the LMB’s Structural Studies Division, has been awarded the Royal Society Francis Crick Medal and Lecture 2016. The medal was awarded for his major and widespread contributions to computational biology. Many human diseases develop when regulatory processes fail. Madan’s research aims to decipher the basis for this. His group […]
How phosphorylated ubiquitin activates Parkin
Early-onset Parkinson’s disease arises when the Parkin protein, an E3 ubiquitin ligase, cannot be activated and remains in a permanently ‘off’ state in neurons. Despite the importance of Parkin activation, until recently no-one has understood how the protein could be switched on. David Komander’s group, in the LMB’s Protein and Nucleic Acid Chemistry Division, has […]