The annual Eastern Region Crystal Growing Competition for Schools has been hosted at the LMB since 1998. The competition, designed to inspire children with a love of science, invites school pupils to grow crystals of potash alum over a five-week period. The pupils then send their best crystals to the LMB for judging. This year, […]
Crystal Growing Competition for schools: winning pupils visit the LMB
The origin of biological clocks
Review of research, including that of the LMB’s John O’Neill, on the evolutionary story of circadian rhythms. More…
Harnessing computer power to understand biology
In an interview for Science Careers, former LMB Group Leader Sarah Teichmann talks about how she was inspired by computational biology by Cyrus Chothia, with whom she did her PhD. She also shares how she gained her skills and abilities and what doors they opened to her. More…
First RNAi meiosis screen in mammals reveals genes essential to generate eggs
During fertilisation, an egg and a sperm fuse to form a new embryo. To create the egg, a precursor cell called an oocyte undergoes meiosis: a specialised form of cell division in which half the chromosomes are separated away leaving exactly the right number of chromosomes in the egg. Meiosis in human oocytes is highly […]
Revealing how GPCRs activate Gα proteins.
G protein coupled receptor (GPCR) mediated signalling is one of the largest and the most diverse signalling pathways in cellular systems. Human GPCRs sense various signals and activate different Gα proteins to trigger distinct cellular responses. This signalling pathway is important for a broad range of processes such as regulation of the immune system, neurotransmission, […]
Structure of the human 20S proteasome with a ligand revealed by cryo-EM
The proteasome is a protein recycling complex that plays a critical role in the smooth running of our cells. It is present in all multicellular organisms and facilitates cell renewal and the controlled death of damaged cells. Paula da Fonseca, from the LMB’s Structural Studies Division, and Edward Morris, from the Institute of Cancer Research, […]