MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Cambridge scientists unlock cause of some types of infertility

Cambridge scientists unlock cause of some types of infertility

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LMB’s Melina Schuh, in collaboration with Bourn Hall Clinic, may have found the cause of some types of infertility, including recurrent miscarriage, after new research found some human eggs carry the wrong number of chromosomes. This article is no longer available from the source website: Cambridge News 19 June 2015

Atomic structure of the anaphase-promoting complex (APC/C)

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The anaphase-promoting complex (APC/C) is an unusually large multi-subunit complex that has a key role in cell division, controlling chromosome segregation and the cell cycle. Using electron cryo-microscopy (cryo-EM), David Barford and his group in the LMB’s Structural Studies Division have solved the first atomic structure of the APC/C, revealing its molecular architecture in unprecedented […]

Megan Davies awarded MBE in Queen’s Birthday Honours

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The LMB is delighted to congratulate Megan Davies on being awarded the MBE in the 2015 Queen’s Birthday Honours. Megan has been the Head of the Medical Research Council Centre, Cambridge since 1996, providing administrative, infrastructure and strategic support and guidance to all the MRC Units in the Cambridge region. In this role, she oversaw […]

Human egg defects caused by error-prone spindle assembly

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Miscarriages and genetic disorders, such as Down’s syndrome, are often caused by errors when an egg develops from its progenitor cell, the oocyte. Most defects occur during meiosis, a specialised form of cell division that leads to the formation of an egg. To ensure the egg cell has exactly the right number of chromosomes, an […]

Joan A. Steitz: A place in the lab, and in biochemistry history

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The pioneering career of LMB Alumnus Joan Steitz, currently Sterling Professor of Molecular Biophysics and Biochemistry at Yale University is featured by CTNOW, looking at her work and how Joan’s time at the LMB studying ribosomes led to her important discoveries in RNA research. More…