Scientific Seminars

Below is a list of upcoming seminars at the LMB aimed at a general scientific audience and open to individuals throughout Cambridge. If you are not at the LMB and wish to attend a seminar, please contact Nikki Dominguez.

The LMB hosts ‘The LMB Seminar Series’, where 1-2 leading scientists per month are invited to speak throughout the year. Four of these lectures are named in honour of LMB Nobel Laureates Max Perutz, Francis Crick, César Milstein and John Kendrew, given by eminent scientists from around the world. The LMB Seminar talks and LMB Named Seminar talks are advertised widely throughout the local area and are open to all.

2017 LMB Seminar Series speakers (click to expand)

  • Caroline Dean – 4pm, 27th April (2016 Perutz Lecture)
  • Jennifer Lippincott-Schwartz – 4pm, 8th May
  • Dan Durocher – 11am, 15th May
  • Andreas Matouschek – 3rd July
  • Chris Lima – 11am, 14th July
  • Patrick Cramer – 4pm, 5th September
  • Jack Szostak – 4pm, 7th September (Crick Lecture)
  • Susan Lea – 11am, 4th October
  • Erin O’Shea – 11am, 15th November (Perutz Lecture)
  • Michelle Dunstone – 12th December

 

A full list of LMB Named Lectures to date can be found here.

Details of other local seminars can be found here


  • Max Perutz Lecture- Antisense transcription and epigenetic switching

    Speaker: Caroline Dean, John Innes Centre, Norwich
    Host: Mariann Bienz
    Date: 27/04/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.

    Further information

    What quantitatively regulates gene expression? Non-coding transcription and chromatin regulation are now seen as major factors regulating gene expression in most eukaryotic genomes. Through the study of how plants time developmental transitions, we have discovered that Arabidopsis floral repressor FLC is an excellent system in which to dissect how non-coding RNA and chromatin mechanisms regulate gene expression. FLC expression is quantitatively modulated by an antisense-mediated chromatin mechanism that coordinately influences transcription initiation and elongation. Expression is then epigenetically silenced through a cold-induced, cis-based, Polycomb switching mechanism. The talk will describe our latest understanding of these conserved mechanisms and how they have been modulated during adaptation. 

  • Infammasomes at the crossroads of innate and cell-autonomous immunity

    Speaker: Petr Broz, University of Basel
    Host: Immunology and Medicine Seminar Series, LMB and CIMR
    Date: 28/04/2017 at 1:00pm in the Max Perutz Lecture Theatre, LMB.


  • Clare Hall King Lecture- Cell Type and Cell State in Development

    Speaker: Marc Kirschner, Harvard Medical School
    Host: Lori Passmore
    Date: 04/05/2017 at 4:00pm in the Max Perutz Lecture Theatre, LMB.

    Further information

    There will be a drinks reception after the seminar.

  • Mulitispectral imaging to uncover the organelle interactome

    Speaker: Jennifer Lippincott-Schwartz, National Institute of Health, Maryland, USA
    Host: Ben Nichols and Bill Schafer
    Date: 08/05/2017 at 4:00pm in the Max Perutz Lecture Theatre, LMB.


  • Annual Sir John Walker Lecture

    Speaker:
    Host: MRC Mitochondrial Biology Unit- Penny Peck
    Date: 11/05/2017 at 4:30pm in the Max Perutz Lecture Theatre, LMB.


  • Agonistic interaction as a strategic action choice process

    Speaker:
    Host: Greg Jefferis
    Date: 12/05/2017 at 10:30am in the Klug Seminar Room, Level 2, LMB.


  • Charting the response to DNA damage

    Speaker: Dan Durocher, University of Toronto, Faculty of Medicine
    Host: Lori Passmore
    Date: 15/05/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.

    Further information

    The orchestration of DNA repair is of fundamental importance to the maintenance of genomic integrity and tumour suppression. DNA damage must be detected in the context of the varied chromatin landscape, its presence must be communicated throughout the cell to alter many ongoing processes, and the machinery that will mend the lesion must be recruited to the damage site. Our understanding of the pathways involved in the DNA damage response in human cells is often the result of pioneering studies in genetically-tractable organisms or through the identification of gene mutations causing genome instability syndromes. With the advent of CRISPR/Cas9-based gene editing, there is an opportunity to prospectively chart the response to DNA damage in human cells. During my presentation, I will present our efforts to map the genetic networks that govern the DNA damage response and will particularly discuss our work aimed at mapping the genetic architecture of the response to PARP inhibitors. Our work revealed new types of genetic vulnerabilities to PARP inhibition and in particular, I will discuss a type DNA lesion that could act as the elusive inhibited-PARP “trap”.

  • LMB cryo-EM course - Past, present and future of cryo-EM

    Speaker: Richard Henderson, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 19/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Physics and Optics

    Speaker: Chris Russo, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 20/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Image formation, Fourier transform, CTF

    Speaker: Paula da Fonseca, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 21/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Data acquisition

    Speaker: Christos Savva, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 22/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Sample preparation

    Speaker: Lori Passmore, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 23/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Image refinement

    Speaker: Sjors Scheres, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 26/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Data analysis strategy

    Speaker: Rafael Fernandez Leiro, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 27/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Modelling and validation

    Speaker: Alan Brown, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 28/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Tomography

    Speaker: John Briggs, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 29/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • LMB cryo-EM course - Our facility and training

    Speaker: Shaoxia Chen/Giuseppe Cannone, MRC LMB
    Host: Sjors Scheres, MRC LMB
    Date: 30/06/2017 at 9:30am in the Max Perutz Lecture Theatre, LMB.


  • Annual AWiSE-LMB Lunchtime Careers Meeting

    Speaker: Various
    Host: Cambridge AWiSE-LMB
    Date: 30/06/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.

    Further information

    More info to follow including registration

  • LMB Seminar-Title to follow

    Speaker: Andreas Matouschek, Northwestern University, USA
    Host: Madan Babu
    Date: 03/07/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.


  • LMB Seminar Series- Title to follow

    Speaker: Chris Lima
    Host: David Komander
    Date: 14/07/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.


  • LMB Seminar Series-Title to follow

    Speaker: Patrick Cramer, Max Planck Institute
    Host: Phil Holliger
    Date: 05/09/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.


  • Crick Lecture-title to follow

    Speaker: Jack Szostack, Harvard, USA
    Host: Phil Holliger
    Date: 07/09/2017 at 4:00pm in the Max Perutz Lecture Theatre, LMB.


  • LMB Seminar-Title to follow

    Speaker: Susan Lea,
    Host: Andrew Carter
    Date: 04/10/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.


  • Max Perutz Lecture

    Speaker: Erin O Shea, Howard Hughes Medical Institute
    Host: Liz Miller
    Date: 15/11/2017 at 11:00am in the Max Perutz Lecture Theatre, LMB.