LMB In The News


Flash frozen under the electron microscope: Examining the mechanical properties of Alzheimer’s amyloid fibrils

“By using electron microscopic images of flash frozen samples, researchers have now been able to examine the exact structure of Alzheimer’s amyloid fibrils and to assess their mechanical properties. As the team reports in the journal Angewandte Chemie, the fibrils are very stiff — one of the underlying causes of their pathogenicity. Because amyloid fibrils are very difficult to analyze with traditional biophysical techniques, Marcus Fändrich (Max Planck Unit for Enzymology of Protein Folding, Halle/Saale, Germany), Carsten Sachse (MRC Laboratory of Molecular Biology, Cambridge, UK), and Nikolaus Grigorieff (Brandeis University, Waltham, USA) were forced to take another approach: They examined Alzheimer’s amyloid fibrils by electron cryomicroscopy.” More…

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Venki Ramakrishan chosen for ‘Padma Vibhushan’, India’s highest civilian award

“Padma Awards, the country’s highest civilian awards, are conferred in three categories, namely, Padma Vibhushan, Padma Bhushan and Padma Shri… ‘Padma Vibhushan’ is awarded for exceptional and distinguished service. The awards are announced on the occasion of Republic Day every year and are conferred by the President of India at a function held at Rashtrapati Bhavan sometime around March/ April…” More…

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Nobel Prize winners visit Downing Street

“British winners of the prestigious Nobel Prize have gathered at Downing Street to celebrate their achievements … Guests included recent winner Venkatraman Ramakrishnan, a structural biologist at the MRC Laboratory of Molecular Biology in Cambridge, who received the 2009 Nobel Prize in Chemistry…” More…

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3D structure of PI3Kdelta: An important drug target for a wide range of diseases

“Intellikine announced today the publication of an article entitled, “The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors,” now available as an advanced online publication at Nature Chemical Biology…The pioneering work was the result of a collaboration led by Roger Williams, Ph.D., Professor in the Laboratory of Molecular Biology at the Medical Research Council in Cambridge, U.K., and it included scientists from the University of California, San Francisco, Intellikine in La Jolla, California, and Merck-Serono Research Center in Geneva, Switzerland.” More…

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An Austrian biotech firm that moved into Cambridge in 2008 has raised £7.2m (EUR 8m)

“f-star, which has developed novel antibody engineering technology, moved to the Babraham Research campus in March 2008 in order to build closer links with the Medical Research Council’s Laboratory of Molecular Biology (LMB) in Cambridge – an acknowledged world leader in antibody science.” More…

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