MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.
To mark World TB Day, Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB), discusses her career journey, the inspiration behind many of her key tuberculosis findings, and her approach to mentoring in the lab. More…
Marta Zlatic and Albert Cardona’s groups in the LMB’s Neurobiology Division (also at the University of Cambridge) have unveiled the first complete map of a fruit fly brain, including all its neurons and connecting synapses. This connectome offers new insights into the brain and will serve as a reference brain, allowing researching to study neurological diseases in greater detail. More…
Kate McDole, Group Leader in the LMB’s Cell Biology Division, discusses how she has developed an adaptive microscope to track cell movement in mice embryos, including design considerations to control factors including specimen movement, angle of light source and positions of optical elements. More…
New research from Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB), has shown that drugs commonly used to treat heartburn could shorten treatment time of tuberculosis (TB), as well as reduce the likelihood of TB bacteria becoming drug resistant. More…
Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB) have discovered that the biological mechanisms which underpin Gaucher disease – a rare genetic disease which is most commonly found amongst Ashkenazi Jews – are also effective at clearing tuberculosis infection. More…
The Cambridge Independent reports on a study from Leo James’ group in the LMB’s PNAC Division which has identified the process whereby HIV-1 builds its capsid using the metabolite IP6 which is captured from cells with a net-like protein lattice. More…