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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Alan Fersht and Wes Robertson discuss the past, present and future of protein studies

The Naked Scientists podcast covers all things protein, including speaking to Alan Fersht and Wes Robertson from the LMB’s PNAC Division. They cover how early advances at the LMB revolutionised the field of protein studies, and how protein design could be developed to address key concerns in health and the environment. More…

Published on 4th July, 2025

First patient treated for APDS, a rare inherited disorder identified by collaborative Cambridge team including Roger Williams’s group

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In 2013, Roger Williams’s group in the LMB’s PNAC Division published findings from a study conducted with researchers at the University of Cambridge, the Babraham Institute and clinicians from Addenbrooke’s Hospital. Together, the team identified a rare genetic mutation which causes a condition now known as Activated PI3K-d Syndrome (APDS), which weakens the immune system and increases vulnerability to severe lung infections. Recently, Mary Catchpole received the first approved treatment for APDS, leniolisib, at Addenbrooke’s Hospital. More…

Published on 27th June, 2025

Sortera Bio has raised £7.5m pre-seed investment from AstraZeneca, BioNTech and CIC

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Business Weekly reports that Sortera Bio, an LMB spinout company, has attracted backers for a £7.5m pre-seed round to power AI models for drug discovery. The round was led by Cambridge Innovation Capital (CIC) with participation from AstraZeneca and BioNTech. More…

Published on 10th June, 2025

The LMB licences ‘tRNA Display’ technology to Constructive.Bio

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Business Weekly reports that Constructive.Bio, an LMB spinout company based on Jason Chin’s research, now holds the exclusive licence to ‘tRNA Display’ technology. The company can start a full commercial rollout of its platform – enabling next-gen synthetic protein engineering applications for pharma, agriculture and advanced materials. More…

Published on 6th June, 2025

2025 IUBMB Jubilee Award Lecture given to Anne Bertolotti

Anne Bertolotti, Group Leader and Joint Head of the LMB’s Neurobiology Division, has been announced as the 2025 recipient of the Jubilee Award Lecture from the International Union of Biochemistry and Molecular Biology (IUBMB) in recognition of her research on protein quality control mechanisms. More…

Published on 7th May, 2025

Emmanuel Derivery on winning the Hooke Medal, how to manage an inter-disciplinary research group, and the exciting field of protein design

Emmanuel Derivery, Group Leader in the LMB’s Cell Biology Division, speaks to the Journal of Cell Science on the motivations behind his career as a researcher studying fundamental cellular processes, his international collaborations in the field of protein design, and the advice he’d give to scientists looking to start their own research groups. More…

Published on 17th April, 2025
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