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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Scientists establish a comprehensive protein interactions map of the replication machinery of a chronic virus

Chronic viral infections are amongst the biggest threats to human health worldwide. Leo James’ group from the LMB’s PNAC Division, in collaboration with scientists at the Austrian Academy of Sciences and University of Basel, have established the first comprehensive overview of cellular proteins interacting with the LCMV polymerase. It is hoped that the research leads to a better understanding of how chronic viral infections start and the complex molecular interactions between viruses and their hosts. More…

Published on 21st December, 2017

Distinct human mutations can alter the effect of medicine

University of Copenhagen logo

About one third of all medicine binds to the same type of receptor in the human body. An estimated 3 percent of the population have receptors of this type that are so genetically different that they are predisposed to altered, ineffective or adverse responses to medicine, a new study from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge shows.  More…

Published on 19th December, 2017

GPCR structures aided drug design

Chemical & Engineering News (C&EN)

A decade after a key structural analysis, scientists have a better understanding of the pharmaceutically important family of receptor proteins – G protein-coupled receptors (GPCR).  Includes reference to the work done at the LMB by Chris Tate. More...

Published on 18th December, 2017

Potassium is critical to circadian rhythms in human red blood cells

An innovative new study from the University of Surrey and John O’Neill’s group from the LMB’s Cell Biology Division has uncovered the secrets of the circadian rhythms in red blood cells and identified potassium as the key to unravelling the mystery. More…

Published on 14th December, 2017

LMB postdoc, Tobias Wauer, wins the 2017 EMPRIS Award for Research in Brain Diseases

LMB postdoctoral researcher, Tobias Wauer, has won the 2017 EMPRIS Award for Research in Brain Diseases for his work on the molecular causes of Parkinson’s disease. In this interview, he explains his fascination for research. More…

Published on 13th December, 2017

LMB scientist, Glenn Masson, spends a week shadowing MP for Cambridge, Daniel Zeichner, through the Royal Society’s Pairing Scheme

Glenn Masson has spent a week shadowing Daniel Zeichner, MP for Cambridge, through the Royal Society’s Pairing Scheme, an initiative which pairs scientists with MPs to foster exchange of knowledge and understanding of politics, policy and science. This article is no longer available from the source website: Cambridge Network December 2017

Published on 13th December, 2017
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