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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Dementia – how close are we to having effective treatments?

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Cambridge Neuroscience, of which the LMB is a part, plays a key role in coordinating dementia research across the large and diverse community of neuroscientists in Cambridge, helping scientists and clinicians work together. The organisation has produced a new film describing some of the progress now being made against this devastating disease, including commentary from Michel Goedert, group leader in the LMB’s Neurobiology Division, who discovered how tau fibres twist together to form tangles, a hallmark of Alzheimer’s, a type of dementia. More…

Published on 18th January, 2017

A chain of events

Linear ubiquitin chains whose very existence once was debated, now are known to play a critical role in an inflammatory disease, thanks to the discovery of an enzyme. David Komander’s group from the LMB are amongst a group of scientists researching the enzymes of the ubiquitin system, which has already shown how mutations in the gene for OTULIN, an enzyme belonging to the OTU family of deubiquitinases, cause a rare systemic inflammatory disease. More…

Published on 6th January, 2017

Cell scientist to watch – Madeline Lancaster

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Madeline Lancaster, group leader in the LMB’s Cell Biology Division, is interviewed by the Journal of Cell Science and describes her impetus to pursue a career in science, discusses starting her own lab at the LMB and talks about her current research. More…

Published on 4th January, 2017
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