MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.
A recent paper from Benjamin Ryskeldi-Falcon’s group reveals the first atomic structure of TDP-43 filaments from the brains of people with ALS and FTD diseases. The discovered structure possesses a unique double-spiral fold at its core, differentiating it from all other amyloidogenic proteins observed so far. More…
“It’s going to change the whole dynamic and hopefully eliminate this bottleneck as well as providing this new grid design for the world.”
Chris Russo and PhD student, Katerina Naydenova, are interviewed by the Cambridge Independent on their exciting new optimisation method for making cryo-EM grids. More…
Established poet, Liz Berry, makes a virtual tour of Buzz Baum’s lab to inspire a new poem, exploring how dreaming lies at the heart of science. More…
Cell Biology Group Leader, John O’Neill, discusses his group’s recent paper. Their work highlights how heart cells regulate daily function through fluctuations in ion levels. Beginning at 47:00. More…
Group Leader John Sutherland discusses his argument that solar UV light is the energy source required to drive the chemical reactions that make the building blocks of life. More…
Cell Biology Group Leader Madeline Lancaster discusses how her ‘failed’ attempt to grow neural stem cells led to the development of brain organoids – miniature brain tissues – which she uses in her research today to better understand the human brain. More