Kate McDole, Group Leader in the LMB’s Cell Biology Division, discusses how she has developed an adaptive microscope to track cell movement in mice embryos, including design considerations to control factors including specimen movement, angle of light source and positions of optical elements. More…
Kate McDole on developing smart microscopes
Heartburn drug could be effective TB treatment
New research from Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB), has shown that drugs commonly used to treat heartburn could shorten treatment time of tuberculosis (TB), as well as reduce the likelihood of TB bacteria becoming drug resistant. More…
Gaucher disease may offer Ashkenazi Jews protection against TB
Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB) have discovered that the biological mechanisms which underpin Gaucher disease – a rare genetic disease which is most commonly found amongst Ashkenazi Jews – are also effective at clearing tuberculosis infection. More…
Enhanced understanding of how HIV-1 infect our cells
The Cambridge Independent reports on a study from Leo James’ group in the LMB’s PNAC Division which has identified the process whereby HIV-1 builds its capsid using the metabolite IP6 which is captured from cells with a net-like protein lattice. More…