![: IDR-Screen helps to identify functional segments in disordered protein regions (dark proteome)](https://www2.mrc-lmb.cam.ac.uk/wordpress/wp-content/uploads/Madan_IoR_may_18-150x150.jpg)
Work from Madan Babu’s group in the LMB’s Structural Studies Division, spearheaded by Charles Ravarani and in collaboration with Alexandre Erkine’s group at Butler University, has for the first time harnessed next generation sequencing and machine learning to develop a high throughput screen to uncover disordered regions of proteins that are functional within cells.
Proteins, the molecular machines of the cell, are formed from chains of amino acids.