![Cytosolic antibody receptor and ubiquitin ligase TRIM21](https://www2.mrc-lmb.cam.ac.uk/wordpress/wp-content/uploads/James_IoR_12-20_Trim-21-sq-150x150.jpg)
Our immune system generates a strong antibody response against nucleoproteins, but the role of this has not been understood. Leo James’ group has revealed a new mechanism that could have important implications for SARS-CoV-2 vaccination and treatment.