MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.
In long feature format, Science Magazine profiles structural biology scientists at the LMB, including Chris Russo and Nobel Prize winner Richard Henderson, and their work on bringing cryo-EM to hundreds of more labs. At present, top-of-the-line cryo-EM machines cost almost $7 million. But with these scientists’ vision, persistence and focussed research, cryo-EM might just become the way we look into the molecular world. More…
Proof-of-principle research led by Chris Russo showing that cryo-EM could be made 10 times cheaper is highlighted by the MRC. “Our goal is to make cryo-EM available to any laboratory that needs it” said Chris. More…
Georgina Ferry looks back at the life of Cyrus Chothia and the importance of his work in laying the foundations of the field of bioinformatics. More…
Venki describes the importance of Max’s work in laying the foundations of molecular and structural biology and in the origin of the LMB. More…
Chris Russo, Katerina Naydenova and Greg McMullan discuss the latest developments in the field of cryo-EM with Paul Brackley of the Cambridge Independent. “Based on this research, several companies and research groups are now working to make this technology widely available, as part of a simple cheap microscope that any biology lab will be able to afford,” said Chris. More…
This Nature opinion piece recounts the dramatic impact of the pivotal 1975 paper by Köhler–Milstein on biomedical and, specifically, immunological research, which was propelled by scientific developments that occurred around the time the paper appeared. It also chronicles the research on monoclonal antibodies over the years all the way to Greg Winter’s research, which features in the story as a podcast. More…