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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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A splice of life – Chemistry World looks at how structural biology has revealed the secrets of the spliceosome

Clare Sansom describes the history of spliceosome research and its importance, focusing on the work of Kiyoshi Nagai and his group. More…

Published on 24th March, 2020

Is cryo-EM taking over structural biology?

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This news story in Nature maps the revolutionary technique’s eventful journey in the structural biology field since 2012-13. Ewen Callaway, on the occasion of the submission of the 10,000th cryo-EM structure in the EMDB, spoke to LMB scientists Richard Henderson and Sjors Scheres. Richard estimates that by 2024, more protein structures will be determined by cryo-EM than by X-ray crystallography. More…

Published on 11th February, 2020

Science Magazine dives into the science behind affordable cryo-EM

In long feature format, Science Magazine profiles structural biology scientists at the LMB, including Chris Russo and Nobel Prize winner Richard Henderson, and their work on bringing cryo-EM to hundreds of more labs. At present, top-of-the-line cryo-EM machines cost almost $7 million. But with these scientists’ vision, persistence and focussed research, cryo-EM might just become the way we look into the molecular world. More…

Published on 24th January, 2020

Slashing energy could make Nobel prize-winning cryo-EM microscopes more affordable

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Proof-of-principle research led by Chris Russo showing that cryo-EM could be made 10 times cheaper is highlighted by the MRC. “Our goal is to make cryo-EM available to any laboratory that needs it” said Chris. More… 

Published on 2nd January, 2020

Cyrus Chothia (1942 – 2019) – Obituary in the Guardian

Georgina Ferry looks back at the life of Cyrus Chothia and the importance of his work in laying the foundations of the field of bioinformatics. More…

Published on 16th December, 2019

People of Science: Venki Ramakrishnan discusses Max Perutz with Brian Cox

graphic image of bbc.co.uk/iplayer text

Venki describes the importance of Max’s work in laying the foundations of molecular and structural biology and in the origin of the LMB. More…

Published on 11th December, 2019
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