MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.
Cambridge Independent feature story on Julian Gough’s new phenotype prediction genome data study, which is also exploring whether DNA genotype can be used to predict Covid-19 risk factors. Julian is asking those who have had consumer DNA tests to aid the research by volunteering their data. More…
Clare Sansom describes the history of spliceosome research and its importance, focusing on the work of Kiyoshi Nagai and his group. More…
This news story in Nature maps the revolutionary technique’s eventful journey in the structural biology field since 2012-13. Ewen Callaway, on the occasion of the submission of the 10,000th cryo-EM structure in the EMDB, spoke to LMB scientists Richard Henderson and Sjors Scheres. Richard estimates that by 2024, more protein structures will be determined by cryo-EM than by X-ray crystallography. More…
In long feature format, Science Magazine profiles structural biology scientists at the LMB, including Chris Russo and Nobel Prize winner Richard Henderson, and their work on bringing cryo-EM to hundreds of more labs. At present, top-of-the-line cryo-EM machines cost almost $7 million. But with these scientists’ vision, persistence and focussed research, cryo-EM might just become the way we look into the molecular world. More…
Proof-of-principle research led by Chris Russo showing that cryo-EM could be made 10 times cheaper is highlighted by the MRC. “Our goal is to make cryo-EM available to any laboratory that needs it” said Chris. More…