Roger Highfield, Science Director at the Science Museum, speaks to the LMB’s Greg Winter about his earliest scientific memories, how a road rage attack redirected his research to focus on protein engineering of antibodies and the day he found out he’d won the Nobel Prize in Chemistry. More…
Greg Winter on innovation in science, his research on phage display and its therapeutic impact, and winning the Nobel Prize
Redefining human brain temperature and its clinical utility
Magnetic resonance spectroscopy allowed Nina Rzechorzek (member of the O’Neill group, Cell Biology) and collaborators to create a HEATWAVE map, showing how temperatures vary in the brain across the day, between the sexes, and as we age – a healthy brain is remarkably hotter than previously assumed. More…
Michel Goedert discusses his life and career in research with DZNE
To mark the award of the Hartwig Piepenbrock-DZNE Prize for his ground-breaking research into the molecular basis of neurodegenerative diseases, DZNE have released a video portrait of Michel Goedert, Group Leader in the LMB’s Neurobiology Division. More…
LMB in vitro testing highlights bicyclic peptides (Bicycle®) as potential antiviral compounds against SARS-CoV-2
Bicycle Therapeutics reports on its updated preclinical data produced in collaboration with Leo James’ group in the LMB’s PNAC Division. In vitro tests of their proprietary bicyclic peptide show promise for antiviral modality against SARS-CoV-2. More…
LMB research featured in summary of three cryo-EM studies of TMEM106b fibrils found in neurodegenerative diseases
Alzforum summarises three recent papers which analysed TMEM106b amyloid filaments in the human brain – including research from Sjors Scheres’ and Michel Goedert’s groups in the LMB’s Structural Studies and Neurobiology Divisions respectively. More…
Structural analysis of GABAA receptors reveals unexpected diversity of arrangements
The Cambridge Independent reports on a recent paper from Radu Aricescu’s group in the LMB’s Neurobiology Division. His group’s structural investigation into type A gamma-aminobutyric acid receptors has found that their subunit arrangements are far more varied than previously thought. More…