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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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What are mini brains?

Shielded by our thick skulls and swaddled in layers of protective tissue, the human brain is extremely difficult to observe in action. Luckily, scientists can use brain organoids – pencil-eraser-sized masses of cells that function like human brains but aren’t part of an organism – to look closer. Madeline Lancaster, from the LMB’s Cell Biology Division, discusses how this is done and whether it is ethical through a video created by TED-Ed. More…

Published on 17th January, 2018

Unlocking the secrets of the brain

Madeline Lancaster, from the LMB’s Cell Biology Division, discusses how lab-grown ‘mini-brains’ could be the key to solving the biggest mysteries about human brain development and disease. More…

Published on 15th January, 2018

The circadian rhythm of life

John O’Neill, from the LMB’s Cell Biology Division, discusses how unravelling the complex mechanisms of the body clock has led to some fascinating discoveries worthy of the 2017 Nobel Prize in Physiology or Medicine. More…

Published on 11th January, 2018

Magnetic attraction of AstraZeneca to MRC LMB

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AstraZeneca has moved it Nuclear Magnetic Resonance laboratory to the LMB while its new global R&D centre is built nearby. More…

Published on 8th January, 2018

Alcohol can cause irreversible genetic damage to stem cells, says study

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Link between drinking and cancer clarified by study – led by KJ Patel’s group in the LMB’s PNAC Division – which indicates alcohol causes cancer by scrambling DNA in cells, eventually leading to mutations. More…

Published on 5th January, 2018

Scientists establish a comprehensive protein interactions map of the replication machinery of a chronic virus

Chronic viral infections are amongst the biggest threats to human health worldwide. Leo James’ group from the LMB’s PNAC Division, in collaboration with scientists at the Austrian Academy of Sciences and University of Basel, have established the first comprehensive overview of cellular proteins interacting with the LCMV polymerase. It is hoped that the research leads to a better understanding of how chronic viral infections start and the complex molecular interactions between viruses and their hosts. More…

Published on 21st December, 2017
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