Ribosome reader to Royal Society leader: a biologist’s road to the Nobel – Nature’s review of LMB group leader Venki Ramakrishnan’s account of his career. More…
Nature reviews Venki Ramakrishnan’s new book
Structure of Pick’s tau distinct from AD tau
In recent years, support has grown for the idea that the same aggregating protein can fold up into different toxic shapes, giving rise to distinct neurodegenerative diseases. Now, in the August 29 Nature, researchers led by Michel Goedert and Sjors Scheres at the MRC Laboratory of Molecular Biology in Cambridge, England, in collaboration with Bernardino Ghetti and colleagues at Indiana University School of Medicine in Indianapolis, provide the first molecular-level proof that this happens. More…
The legacy of Fred Sanger – 100 years on from 1918
August 2018 marks the centenary of the birth of Frederick (Fred) Sanger (1918–2013), one of the most influential scientists of the 20th century. Few scientists transform a discipline in their lifetime. Fred Sanger did this, not once but twice. By devising methods for sequencing, he revolutionized our understanding of both proteins and nucleic acids gaining the Nobel Prize in Chemistry twice. He is the only scientist to have achieved this honour. More…
Complete fly brain images at nanoscale resolution
A neuroscience milestone: a high-resolution digital snapshot of the adult fruit fly brain. Researchers can now trace the path of any one neuron to any other neuron throughout the whole brain. The research, lead by a team of scientists at the Howard Hughes Medical Institute’s Janelia Research Campus, required the collaboration of dozens of other scientists, including at Johns Hopkins University and in Greg Jefferis group at the MRC Laboratory of Molecular Biology. More…
Drug designers embrace electron cryo-microscopy
Electron cryo-microscopy is enabling drug designers to understand how protein targets in the body interact with potential therapeutics. Technology developed at LMB, such as sensitive detectors and analytical software, as well as collaborations between LMB scientists and industry is helping make this possible. More…
The epic hunt for the place on Earth where life started
Working out how and where life began is one of the greatest puzzles to solve. The LMB’s Philipp Holliger and John Sutherland, and others, discuss their theories on how the first life arose. More…