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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Tau filaments from the Alzheimer’s brain revealed

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Tau filaments isolated from an Alzheimer’s brain are the latest, high-profile exploit of cryo-electron microscopy. Crafting a technique that has become his claim to fame, Sjors Scheres of the MRC Laboratory of Molecular Biology in Cambridge, England, teamed up with Michel Goedert, also at MRC, to solve 3.4-Angstrom resolution structures of both straight and paired helical filaments of tau. The structures, first unveiled at the AD/PD meeting in Vienna last March, were formally published in Nature on July 5. More…

Published on 17th July, 2017

Exploring the incredible transport system inside our cells

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Simon Bullock discusses his research into intracellular trafficking of RNA, and talks about the importance of science outreach in inspiring the next generation of young scientists. More…

Published on 13th July, 2017

Sharp focus on Alzheimer’s may help target drugs

Abnormal deposits that build up in the brain during Alzheimer’s have been pictured in unprecedented detail in research led by Sjors Scheres and Michel Goedert. More…

Published on 7th July, 2017

G-protein coupled receptors as drug targets: Heptares Therapeutics celebrates its tenth anniversary

Chris Tate – co-founder of Heptares Therapeutics, a company established to commercialise research from the LMB – discusses his work on G-protein coupled receptors. More…

Published on 6th July, 2017

Cambridge105 coverage of the LMB Open Day

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Interviews with Katja Roper, Andrew Carter and William Schafer at the LMB Open Day. More…

Published on 3rd July, 2017

AstraZeneca and LMB breakthrough on how DNA is repaired

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Using the pioneering technique of cryo-EM, scientists at AstraZeneca and LMB have made a ground-breaking biological discovery that could help develop new cancer treatments. More…

Published on 19th June, 2017
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