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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Dementia – how close are we to having effective treatments?

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Cambridge Neuroscience, of which the LMB is a part, plays a key role in coordinating dementia research across the large and diverse community of neuroscientists in Cambridge, helping scientists and clinicians work together. The organisation has produced a new film describing some of the progress now being made against this devastating disease, including commentary from Michel Goedert, group leader in the LMB’s Neurobiology Division, who discovered how tau fibres twist together to form tangles, a hallmark of Alzheimer’s, a type of dementia. More…

Published on 18th January, 2017

A chain of events

Linear ubiquitin chains whose very existence once was debated, now are known to play a critical role in an inflammatory disease, thanks to the discovery of an enzyme. David Komander’s group from the LMB are amongst a group of scientists researching the enzymes of the ubiquitin system, which has already shown how mutations in the gene for OTULIN, an enzyme belonging to the OTU family of deubiquitinases, cause a rare systemic inflammatory disease. More…

Published on 6th January, 2017

Cell scientist to watch – Madeline Lancaster

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Madeline Lancaster, group leader in the LMB’s Cell Biology Division, is interviewed by the Journal of Cell Science and describes her impetus to pursue a career in science, discusses starting her own lab at the LMB and talks about her current research. More…

Published on 4th January, 2017

HIV Research Breakthroughs 2016

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Medical Daily includes work by the LMB’s Leo James’s group and University College London on improving antiviral drugs as one of its HIV research breakthroughs of 2016. More…

Published on 19th December, 2016

New microscope lens: top ten breakthroughs

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Work by MRC funded Gail McConnell and LMB Emeritus, Brad Amos and colleagues at the University of Strathclyde have been selected for Physics World’s Top Ten Breakthroughs of 2016, for creating a new microscope lens that offers the unique combination of a large field of view with high resolution. Called a mesolens, the device allows a confocal microscope to create 3D images of much larger biological samples than was previously possible – while providing detail at the sub-cellular level. The development of the lens was initiated by Brad Amos at the LMB. More…

Published on 13th December, 2016

Richard Pannell “wins science ‘Oscar’ for his life’s work”

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The Haverhill Echo celebrates local resident Richard Pannell’s MRC Lifetime Achievement CEO Award. Richard, who was nominated by his current supervisor, Andrew McKenzie, has worked at the LMB since 1980. More…

Published on 8th December, 2016
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