Alzforum summarises three recent papers which analysed TMEM106b amyloid filaments in the human brain – including research from Sjors Scheres’ and Michel Goedert’s groups in the LMB’s Structural Studies and Neurobiology Divisions respectively. More…
LMB research featured in summary of three cryo-EM studies of TMEM106b fibrils found in neurodegenerative diseases
Structural analysis of GABAA receptors reveals unexpected diversity of arrangements
The Cambridge Independent reports on a recent paper from Radu Aricescu’s group in the LMB’s Neurobiology Division. His group’s structural investigation into type A gamma-aminobutyric acid receptors has found that their subunit arrangements are far more varied than previously thought. More…
Brad Amos on microscopy design, writing LMB Christmas skits, and diving with sharks
Emeritus scientist Brad Amos is a guest on The Microscopists podcast from Bitesize Bio. Listen to him chat to host Peter O’Toole about his career, experience with microscope design, and insights into the annual LMB Christmas skit. More…
The journey to solving structures
Richard Henderson, from the LMB’s Structural Studies Division, discusses his work and the evolution of structural biology on the Knowable podcast. More…
Cambridge demonstrates how science is improving lives
The LMB recently welcomed George Freeman MP as part of a wider visit to the Cambridge Biomedical Campus to learn how Cambridge is leading innovation in life sciences. During a tour of the LMB with Jan Löwe, Chris Russo and Madeline Lancaster, the Minister saw and learned how developments in low-energy cryo-EM will increase accessibility of this technique worldwide, and how brain organoids are advancing understanding of human brain development and disease. More…
Collaborative LMB study reveals S-shaped structure of Aβ42 filaments in Alzheimer’s disease and other neurodegenerative diseases
A recent structural study led by Sjors Scheres, Michel Goedert and Benjamin Ryskeldi-Falcon’s groups at the LMB has used cryo-EM to detect two main types of Aβ42 filaments from both sporadic and familial Alzheimer’s disease. More…