LMB In The News


Potassium is critical to circadian rhythms in human red blood cells

An innovative new study from the University of Surrey and John O’Neill’s group from the LMB’s Cell Biology Division has uncovered the secrets of the circadian rhythms in red blood cells and identified potassium as the key to unravelling the mystery. More…

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LMB postdoc, Tobias Wauer, wins the 2017 EMPRIS Award for Research in Brain Diseases

LMB postdoctoral researcher, Tobias Wauer, has won the 2017 EMPRIS Award for Research in Brain Diseases for his work on the molecular causes of Parkinson’s disease. In this interview, he explains his fascination for research. More…

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LMB scientist, Glenn Masson, spends a week shadowing MP for Cambridge, Daniel Zeichner, through the Royal Society’s Pairing Scheme

Glenn Masson has spent a week shadowing Daniel Zeichner, MP for Cambridge, through the Royal Society’s Pairing Scheme, an initiative which pairs scientists with MPs to foster exchange of knowledge and understanding of politics, policy and science. More…

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Trim-Away: a new technique for depleting proteins and studying their function

Dean Clift from Leo James’ group, in collaboration with LMB alumnus Melina Schuh at the Max Planck Institute, have developed a new technique – Trim-Away – which allows proteins to be rapidly depleted from cells. By harnessing the cells’ protein degradation machinery and TRIM21, the scientists have provided a new technique for studying protein function. More…

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Finding the founding fathers of molecular biology – a blog post by LMB PhD student, Lisa Strittmatter

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Lisa Strittmatter, PhD student in the LMB’s Structural Studies Division, explores a recent talk given at the LMB by Professor Sir John Meurig Thomas, and the light it sheds on the key scientists involved in the origins of molecular biology. More…

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Brain research in the third dimension

Madeline Lancaster, cell biologist at the MRC Laboratory of Molecular Biology in Cambridge, has developed a technique allowing her to create mini brains from cell cultures. These incredible organoids, no larger than the eraser at the end of a pencil, serve as a model for Madeline’s research into early human brain development and are enabling Madeline and her team to tackle the age-old question: what is it that distinguishes us as humans? More…

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LMB scientist wins ‘Best Technology’ prize in the 2017 Biomaker Challenge

The LMB’s Wolfgang Schmied, in collaboration with Stéphanie Polderdijk from the Cambridge Institute for Medical Research, won ‘Best Technology’ prize in the 2017 Biomaker Challenge for developing a low-cost chromatography system for protein purification. The Challenge aims to show the value of open, low-cost and DIY technologies as convening points for interactions between biologists and engineers. More…

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BBC: Daytime wounds ‘heal more quickly’

A new study led by John O’Neill and Ned Hoyle shows how bodyclocks in skin cells influence wound healing. More…

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Using cryo-EM to solve the structure of a protein complex critical for gene expression

Lori Passmore and her group have used cryo-electron microscopy to solve the structure of CPF, a protein complex critical for gene expression. Understanding the structure and function of intact CPF, and how it is assembled, has been a central question in the field of gene expression for decades. More…

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PINK1 caught on the brink of phosphorylation

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Scientists have caught a rare view of an unusual kinase poised to phosphorylate its substrate. Led by David Komander, MRC Laboratory of Molecular Biology in Cambridge, England, U.K., the researchers reported the crystal structure of the kinase PINK1 bound to ubiquitin in the October 30 Nature.  “We captured a pre-catalytic state, a snapshot of PINK1 holding ubiquitin before the phosphate group jumps on,” said first author Alexander Schubert. More…

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