LMB In The News

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Scientists find first evidence of local clock in the brain

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Research by groups at Imperial College London and Michael Hastings’ group at LMB have revealed how local body clocks control waking and sleeping. A master clock found in part of the brain called the suprachiasmatic nucleus (SCN) is thought to synchronise lots of ‘local’ clocks that regulate many aspects of our metabolism, for example in the liver. But until now scientists have not had sufficient evidence to demonstrate the existence of these local clocks in the brain or how they operate. More…

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Crystal beauty: Illuminating the structure of matter

BBC News

The LMB has played a pivotal role in the development of X-ray crystallography and the inspirational work of crystallographic scientists from round the UK is showcased in an upcoming exhibition at the Royal Albert Hall. “Illuminating Atoms” presents a selection of photographs by Max Alexander, to celebrate the International Year of Crystallography. The exhibition can be viewed on the free open days on 15th, 16th and 29th November, or at performances until 7th December 2014. More…

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Bicycle Therapeutics announces £20M million for drug development

Reuters

Bicycle Therapeutics, founded as a spin out company from the LMB by Sir Greg Winter and Christian Heinis, has secured £20m equity financing to develop bicycle drug candidates for cancer treatment. The bio-therapeutics company has used its bicyclic peptide technology to discover a new class of drug candidates which are similar to antibodies but 100-fold smaller and manufactured using simple, economic chemical synthesis. More…

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Brian Clark 1936-2014

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Professor Brian Clark, member of LMB Scientific Staff 1964-1974, and founder of structural biology research at Aarhus University, died on Monday 6 October 2014 aged 78 years. Brian led the team crystallising tRNA at LMB before moving to Aarhus. He was a very loyal supporter of LMB and recently attended the LMB alumni symposium in Cambridge. More…

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Worm Watch Lab: one year on

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It’s been more than a year since the launch of Worm Watch Lab, a citizen science project involving the LMB’s William Schafer in which members of the public watch videos of tiny nematode worms, to contribute to a neuroscience study. So what has been spotted so far? More…

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New film premieres sparkling history of crystallography

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A new documentary, charting the history of crystallography tells a fascinating story of a scientific technique that is revealing many of life’s most beautiful secrets. The 40 minute film includes exclusive interviews with internationally acclaimed scientists and unique glimpses into rarely seen historical collections. The work of LMB scientists including Kendrew, Perutz, Watson, Crick and Ramakrishnan is mentioned, and the film includes material from the LMB Archive. More…

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NeuroPod – Fly brain tidy-up

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In this Podcast, the LMB’s Greg Jefferis talks to Kerri Smith from Nature about a new algorithm that sorts neurons in the fly brain by type – and finds a few surprises. More…

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Discovery Could Help Turn Antibiotic Into Antimalarial Drug

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Scientists in Melbourne and collaborators led by the LMB’s Sjors Scheres have made progress toward new antimalarial drugs, after revealing how an antibiotic called emetine blocks the molecular machinery that produces the proteins required for malaria parasite survival. More…

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Journal allows authors to update their research

Times Higher Education

The open access journal eLife has launched a new type of article that will allow authors to report significant additions to their original research. LMB group leader, Sjors Scheres, becomes the first author to publish a research advance article, an update on his paper that reported an important step forward in electron cryo-microscopy. More…

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Two LMB Scientists’ archives added to the Wellcome Library

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The archive papers of two former LMB scientists, John Sulston and Alan Coulson, have been added to the Wellcome Library.

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