MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.
Type 2 ILCs (ILC2s) play an important role in dealing with parasites and are implicated in allergy. Andrew McKenzie’s group has discovered that the transcription factor RORα acts as a checkpoint controlling divergence between T cell and ILC2 development.
Emmanuel Derivery’s group, in collaboration with David Baker’s group in Seattle, have, for the first time, re-engineered two proteins so that they assemble into a 2D material and used this design to investigate a fundamental process of cell biology, receptor endocytosis.