MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.
C&EN discusses recent research using the nematode worm C. elegans to examine wireless brain communications using neuropeptides. They include research led by Lidia Ripoll Sanchez in William Schafer’s group in the LMB’s Neurobiology Division, which resulted in the first map of the entire neuropeptide signalling network of C. elegans. More…
Tanmay Bharat, Group Leader in the LMB’s Structural Studies Division, was honoured by the 2024 Blavatnik Awards in the UK as Finalist in the Life Sciences category. In this video Tanmay discusses his research using electron tomography to investigate biofilms and the motivations behind his work. More…
Scott Wilson, PhD student in Albert Cardona’s group in the LMB’s Neurobiology Division, recently appeared on the popular Chinese game show ‘Super Brain’. Representing the UK, Scott took part in a complex challenge on the popular show which is streamed to hundreds of millions of viewers across China. He recently spoke to Wolfson College about his experience. More…
Jason Chin spoke to BBC’s Roland Pease about his group’s new EcORep orthogonal replication system that enables rapid protein evolution in E.coli and how it could help create new substances to be used in medicine & industry. More…
While filaments of either tau or TDP-43 underlie 90% of frontotemporal dementia cases, the proteopathic culprits behind the remaining 10 percent have eluded researchers. Fused in sarcoma (FUS) often forms inclusions in such cases, hence Benjamin Ryskeldi-Falcon’s group and collaborators expected to find FUS fibrils when they put samples from these patients’ brains through the cryoEM ringer. As reported in Nature, they happened upon filaments of another RNA-binding protein, namely TAF15. More…
The latest episode of The EMBO podcast features John O’Neill and Andrew Beale, Group Leader and postdoctoral researcher in the LMB’s Cell Biology Division. They talk about how investigating a mysterious band on a western blot led to a new understanding of the red blood cell’s clockwork mechanism. Read more…