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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Kate McDole on developing smart microscopes

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Kate McDole, Group Leader in the LMB’s Cell Biology Division, discusses how she has developed an adaptive microscope to track cell movement in mice embryos, including design considerations to control factors including specimen movement, angle of light source and positions of optical elements. More…

Published on 15th February, 2023

Heartburn drug could be effective TB treatment

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New research from Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB), has shown that drugs commonly used to treat heartburn could shorten treatment time of tuberculosis (TB), as well as reduce the likelihood of TB bacteria becoming drug resistant. More…

Published on 14th February, 2023

Gaucher disease may offer Ashkenazi Jews protection against TB

Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB) have discovered that the biological mechanisms which underpin Gaucher disease – a rare genetic disease which is most commonly found amongst Ashkenazi Jews – are also effective at clearing tuberculosis infection. More…

Published on 14th February, 2023

Enhanced understanding of how HIV-1 infect our cells

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The Cambridge Independent reports on a study from Leo James’ group in the LMB’s PNAC Division which has identified the process whereby HIV-1 builds its capsid using the metabolite IP6 which is captured from cells with a net-like protein lattice. More…

Published on 27th January, 2023

Nina Rzechorzek on daily brain temperature rhythms

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Nina Rzechorzek, a member of the O’Neill group in the LMB’s Cell Biology Division, was lead author on a paper in Brain earlier this year. This podcast discusses their findings. More…

Published on 16th December, 2022

The age-old problem of telomere maintenance

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Kelly Nguyen, a Group Leader in the LMB’s Structural Studies Division, was awarded the 2022 Eppendorf Award for Young European Investigators earlier this year. In this Nature Portfolio podcast, Kelly discusses her work leading up to the award and future direction in the field. More…

Published on 24th November, 2022
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