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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Michel Goedert discusses his life and career in research with DZNE

To mark the award of the Hartwig Piepenbrock-DZNE Prize for his ground-breaking research into the molecular basis of neurodegenerative diseases, DZNE have released a video portrait of Michel Goedert, Group Leader in the LMB’s Neurobiology Division. More…

Published on 16th May, 2022

LMB in vitro testing highlights bicyclic peptides (Bicycle®) as potential antiviral compounds against SARS-CoV-2

Bicycle Therapeutics reports on its updated preclinical data produced in collaboration with Leo James’ group in the LMB’s PNAC Division. In vitro tests of their proprietary bicyclic peptide show promise for antiviral modality against SARS-CoV-2. More…

Published on 28th April, 2022

LMB research featured in summary of three cryo-EM studies of TMEM106b fibrils found in neurodegenerative diseases

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Alzforum summarises three recent papers which analysed TMEM106b amyloid filaments in the human brain – including research from Sjors Scheres’ and Michel Goedert’s groups in the LMB’s Structural Studies and Neurobiology Divisions respectively. More…

Published on 13th April, 2022

Structural analysis of GABAA receptors reveals unexpected diversity of arrangements

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The Cambridge Independent reports on a recent paper from Radu Aricescu’s group in the LMB’s Neurobiology Division. His group’s structural investigation into type A gamma-aminobutyric acid receptors has found that their subunit arrangements are far more varied than previously thought. More…

Published on 8th April, 2022

Brad Amos on microscopy design, writing LMB Christmas skits, and diving with sharks

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Emeritus scientist Brad Amos is a guest on The Microscopists podcast from Bitesize Bio. Listen to him chat to host Peter O’Toole about his career, experience with microscope design, and insights into the annual LMB Christmas skit. More…

Published on 11th March, 2022

The journey to solving structures

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Richard Henderson, from the LMB’s Structural Studies Division, discusses his work and the evolution of structural biology on the Knowable podcast. More…

Published on 3rd March, 2022
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