![A plate in which a plaque assay has been performed to measure virus quantity in a sample. Cells are stained blue so that holes represent areas where viral infection has occurred](https://www2.mrc-lmb.cam.ac.uk/wordpress/wp-content/uploads/James_ior_7-21_83D0FAB6-9AE1-4D55-BDF4-B8AAB613F2F2_sq-150x150.jpg)
While infected with SARS-CoV-2, our immune systems generate antibodies against both Spike (S) and Nucleoprotein (N). However, standard tests only show neutralisation for S-antibodies. Leo James’ group has developed a new assay that measures anti-viral activity of N-antibodies.