MRC Laboratory of Molecular Biology
One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.
An international team of scientists, including Lalita Ramakrishnan’s group in the University of Cambridge Molecular Immunity Unit, based at the LMB, have discovered that Leprosy hijacks our immune system, turning an important repair mechanism into one that causes potentially irreparable damage to our nerve cells. More…
Ramanujan Hegde talks about protein localization inside cells and quality control of this process. More…
Tau filaments isolated from an Alzheimer’s brain are the latest, high-profile exploit of cryo-electron microscopy. Crafting a technique that has become his claim to fame, Sjors Scheres of the MRC Laboratory of Molecular Biology in Cambridge, England, teamed up with Michel Goedert, also at MRC, to solve 3.4-Angstrom resolution structures of both straight and paired helical filaments of tau. The structures, first unveiled at the AD/PD meeting in Vienna last March, were formally published in Nature on July 5. More…
Simon Bullock discusses his research into intracellular trafficking of RNA, and talks about the importance of science outreach in inspiring the next generation of young scientists. More…
Abnormal deposits that build up in the brain during Alzheimer’s have been pictured in unprecedented detail in research led by Sjors Scheres and Michel Goedert. More…
Chris Tate – co-founder of Heptares Therapeutics, a company established to commercialise research from the LMB – discusses his work on G-protein coupled receptors. More…