![An Owl with caffeine](https://www2.mrc-lmb.cam.ac.uk/wordpress/wp-content/uploads/LMB_Insight_Caffeine_Owl-5x5-150x150.png)
New research by John O’Neill, in the LMB’s Cell Biology Division, and Kenneth Wright, at the University of Colorado, has revealed the mechanism by which caffeine affects the human body clock. The body’s internal clock affects many aspects of human health and disease, such as when we feel sleepy, how we metabolise food, and even when in the day we observe the best athletic and cognitive performance.