Jason Chin

Systematic genetic code reprogramming
Group Leader page

We are developing approaches for systematically reprogramming the genetic code of cells and organisms. These approaches involve engineering the translational machinery of cells and the genome with the goal of rewriting the genetic code for unnatural polymer synthesis.


References:

Wang, K., Fredens, J., Brunner, S. F.,  Kim, S. H.,  Chia, T. and  Chin, J. W.
Defining synonymous codon compression schemes by genome recoding.
Nature  2016 in press

Neumann, H., Wang, K., Davis, L., Garcia-Alai, M. and Chin, J.W. (2010)
Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome.
Nature. 464(7287):441-4.